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Accredited Drug Testing provides a wide range of drug and alcohol tests across our 40 testing facilities in the Midfield, Alabama area. Whether it's DOT or non-DOT urine analysis, breathalyzer tests, EtG alcohol analysis, or hair sampling, we cater to personal, corporate, and legal requirements. In Midfield, AL, rapid testing as well as SAMSA lab-certified analysis are offered, with same-day service options. Many of our testing centers are conveniently located close to your residence or place of work. Our additional offerings include Occupational Health Testing, Clinical Testing, and Background Screening.
Dial (800) 221-4291 or register online to begin. Select your test type and location — services are available for you, your team, or others. With quick and simplified scheduling, you can book through our scheduling department or online at any time. Our simple and efficient system ensures you can organize testing near Midfield with ease.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Midfield drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Midfield, Jefferson County, drug-related arrests have risen by 20% over the past five years.
Midfield, which is in Jefferson County, reported that 15% of high school students have abused prescription drugs at least once.
In Midfield, part of Jefferson County, emergency room visits due to drug overdoses increased by 10% between 2019 and 2022.
Drug abuse accounts for 25% of all criminal activity reported in Midfield, Jefferson County.
Jefferson County Health Department recorded a 5% increase in drug addiction treatment enrollments from Midfield in recent years.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Midfield, AL, recognize the impact of drug abuse on workplace safety and productivity. Many have implemented strict drug testing policies as part of their hiring process and ongoing employment conditions. These policies are supported by the Occupational Safety and Health Administration, ensuring that workplaces remain safe and efficient.
Drug testing is typically conducted through pre-employment screenings, random testing, and for-cause testing when necessary. Companies comply with federal guidelines provided by the U.S. Department of Labor, which helps maintain a drug-free workplace environment.
Employers also offer support programs for employees struggling with addiction, often in collaboration with resources from the Alabama Health Department. By promoting these support mechanisms, companies aim to balance enforcement with compassion.
In efforts to combat drug issues in Midfield, AL, Jefferson County is actively collaborating with state initiatives. The Alabama Department of Public Health provides resources and educational programs to prevent drug abuse and support recovery in the community. The city is also partnering with the U.S. Department of Justice for law enforcement training and funding aimed at tackling illicit drug activities.
Local governments, alongside state agencies, have launched multiple outreach programs to educate residents about the dangers of drug abuse. Initiatives like community forums and school-based awareness campaigns are supported by the Substance Abuse and Mental Health Services Administration, reinforcing the collective effort to curb addiction.
Midfield, AL, has recently seen successful drug busts that disrupted local drug trafficking networks. In a coordinated effort with the Drug Enforcement Administration, local law enforcement seized several kilograms of illicit drugs, resulting in multiple arrests. These operations have significantly impacted the availability of narcotics in the area.
Community involvement remains a crucial factor in identifying and reporting suspicious activities, further aiding police in their crackdown on drug-related crimes. Awareness campaigns continue to inform residents on how they can help law enforcement efforts.
Recent drug-related events in Jefferson County highlight the persistent nature of this challenge. However, with continuous cooperation between residents and law enforcement, Midfield aims to achieve a safer, drug-free environment.
Accredited Drug Testing offers fast, reliable employment screening services in Midfield, AL. Trusted by employers nationwide for accurate results and exceptional service.
Alabama Department of Public Health
Substance Abuse and Mental Health Services Administration
U.S. Department of Justice
Drug Enforcement Administration
Alabama Cooperative Extension System
Alabama Council on Behavioral Healthcare Services
Occupational Safety and Health Administration
U.S. Department of Labor
Alabama Department of Mental Health
Midfield Police Department
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024