Our automated scheduling system is available 24/7. Order your test online and receive your donor/registration pass by email. Click Here
Same Day Service
Accredited Drug Testing delivers extensive drug and alcohol testing solutions at 31 locations around Curtiss, Arizona. Our offerings include DOT and non-DOT urine drug tests, breath alcohol tests, EtG alcohol assessments, and hair drug testing for personal, employer-based, or legal use. In Curtiss, AZ, we ensure prompt result services along with SAMSA certified lab analyses. Enjoy same-day service, with most Curtiss testing facilities conveniently located minutes from your residence or workplace. Other services encompass Occupational Health Testing, Clinical Testing, and Background Checks.
Dial (800) 221-4291 or register online. Choose your desired test, then select a nearby center—whether testing for yourself, an employee, or another individual, it’s Fast and Easy. Contact our scheduling team or set up your test online round the clock. Our efficient and simple system ensures drug testing near Curtiss is scheduled with ease.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Curtiss drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Curtiss, AZ, have diverse policies on drug testing. Most companies perform pre-employment screening to ensure a drug-free workplace. These tests often follow guidelines set by the federal government. More information can be found on the Substance Abuse and Mental Health Services Administration website.
Arizona state law permits random drug testing if the policy is clearly communicated to employees. This is particularly relevant for safety-sensitive jobs. Employers must maintain a non-discriminatory approach as stipulated by the Arizona Industrial Commission, ensuring fairness and compliance with the state's rules and regulations.
Additionally, the federal Department of Transportation requires drug testing for all commercial drivers in Curtiss, AZ. These regulations emphasize safety and are detailed on the U.S. Department of Transportation website. Adhering to these standards helps businesses avoid legal complications and maintain a safe, efficient work environment.
The government in Curtiss, AZ, is actively addressing drug problems through various initiatives. Local efforts include collaboration with the Cochise County Health & Social Services to provide education and preventive programs aimed at reducing substance abuse. The town is also focusing on increasing community awareness and enhancing resources for individuals seeking help.
At the state level, Arizona's involvement is reinforced by the Arizona Department of Health Services, which implements statewide strategies focusing on rehabilitation and recovery assistance. Federal support involves coordination with agencies like the Substance Abuse and Mental Health Services Administration, enabling access to broader resources and funding for local programs.
In Curtiss, AZ, recent collaborative efforts between local law enforcement and regional agencies have led to a significant drug bust. Officers seized large quantities of methamphetamine and arrested several individuals associated with a notorious drug trafficking operation. This operation, months in the making, highlights the community's commitment to curbing illegal drug activities impacting the safety and well-being of its residents.
The drug-related challenges in Curtiss have spurred local groups to amplify educational campaigns on the dangers of substance abuse. These initiatives aim to raise awareness about the signs of drug involvement, particularly among teenagers. By involving local schools and families, Curtiss hopes to foster an environment where young individuals can openly discuss the risks and seek guidance without fear of stigma.
Curtiss Police Department has increased community outreach, inviting residents to participate in neighborhood watch programs. These initiatives are designed to empower citizens in reporting suspicious activities and to aid ongoing investigations. The department emphasizes that resident involvement is crucial for long-term deterrence of drug-related crime, thereby enhancing the safety and cohesion of the town.
In response to the increasing threat of fentanyl, public health officials in Curtiss have intensified efforts to distribute naloxone kits. This strategy is paired with workshops on overdose prevention and the availability of addiction treatment resources. The goal is to equip the community with lifesaving tools while simultaneously promoting support networks vital for recovery journeys.
The recent Curtiss drug interdiction has also prompted law enforcement to focus on dismantling related financial networks. By seizing assets linked to drug trafficking, authorities aim to cripple the financial backbone of these operations. This strategy has proven effective in reducing the allure of the drug trade, sending a strong message to those considering illegal activities.
Accredited Drug Testing offers fast, reliable employment screening services in Curtiss, AZ. Trusted by employers nationwide for accurate results and exceptional service.
Quickly find trusted local drug testing centers in Curtiss, AZ — fast, convenient, and reliable every time!
Quickly find a local DOT drug testing center in Curtiss, AZ — fast, reliable, convenient nationwide service!
DNA testing for legal and non-legal purposes including child support, and child custody around Curtiss, AZ.
Including specimen collector training, DER training, reasonable suspicion training and much more in Curtiss, AZ.v
Get fast, accurate hair drug testing at our convenient Curtiss, AZ locations—results you can trust, every time!
Fast, reliable alcohol testing to keep your workplace safe and compliant every single day in Curtiss, AZ.
Reliable nationwide drug testing services ensuring accuracy, compliance, and quick results for businesses and individuals in Curtiss, AZ.
Accurate 5 panel drug testing with fast, confidential results—trusted by Curtiss, AZ employers and individuals nationwide.
Comprehensive 10 panel drug testing with fast, reliable results—trusted for Curtiss, AZ workplace and personal testing needs.
Convenient on-site mobile drug testing with fast, reliable results—saving time while keeping your Curtiss, AZ workplace compliant.
Certified DOT physicals with quick, reliable exams to keep Curtiss, AZ drivers compliant and on the road with confidence.
Join our DOT consortium for hassle-free compliance, random testing management, and reliable driver safety solutions.
Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024