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At 32 East Foothills locations in California, Accredited Drug Testing provides full-scale drug and alcohol testing solutions. From DOT and non-DOT urine drug assessments to breath and EtG alcohol evaluations, as well as hair drug evaluations, we serve individuals, companies, and legal requirements. Our East Foothills, CA offices offer quick result options and utilize SAMSA-approved labs, with most centers conveniently located for residents and professionals. Additional offerings include Occupational Health Exams, Clinical Analysis, and Background Checks.
Dial (800) 221-4291 or register online to set up your service. Select your preferred test type and find a nearby center—whether for personal, corporate, or third-party testing. With our scheduling team or our 24/7 online portal, organizing your test is a breeze. Our efficient, easy-to-navigate system lets you schedule drug testing in East Foothills with minimal effort.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our East Foothills drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
East Foothills, located in Santa Clara County, saw a 20% increase in opioid-related overdoses from 2019 to 2021.
In 2021, 15% of youth in East Foothills, Santa Clara County, reported past-month illicit drug use.
Santa Clara County reported over 300 drug-related hospitalizations in East Foothills in 2020.
The percentage of methamphetamine-related arrests in East Foothills increased by 25% between 2020 and 2022.
In 2021, Santa Clara County data showed that 12% of adults in East Foothills struggled with substance abuse.
Santa Clara County health surveys revealed a 18% rise in emergency calls due to drug overdoses in East Foothills in 2021.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in East Foothills, CA, recognize the impact of drug abuse on workplace safety and productivity. Many have implemented strict drug-testing policies to maintain a drug-free work environment. Companies engage with local agencies to ensure compliance with state and federal guidelines, following best practices outlined by the U.S. Department of Labor.
Corporate drug testing in East Foothills typically includes pre-employment screenings and random checks for current employees. This approach not only deters substance abuse but also assists employees in seeking help for addiction. Retaining a safe work culture remains a top priority for employers in the area.
The government of East Foothills, CA, in Santa Clara County, has been actively working to combat drug abuse by implementing comprehensive prevention programs. Collaborations between local police and the Santa Clara County Public Health Department aim to reduce the prevalence of substance abuse through awareness campaigns. More about these initiatives can be found on the Santa Clara County Public Health Department website.
State-level efforts include funding from California's Department of Health Care Services to support treatment facilities and programs in East Foothills. These initiatives focus on accessibility and support for those in need of addiction recovery services. For state resources, visit the California Department of Health Care Services.
In East Foothills, CA, local law enforcement conducted a significant drug bust last week, dismantling a major drug trafficking ring. Authorities reported that multiple arrests were made and several kilos of illegal substances were seized during the operation. This effort was part of a broader initiative to reduce drug-related crimes in the community.
Recent months have seen an increase in community reports of suspicious activities, leading to the arrests of individuals involved in illegal drug distribution. The police have intensified patrols and surveillance operations in known hotspots to deter criminal activities and ensure public safety.
East Foothills residents are urged to stay vigilant and report any suspicious activity to authorities. Community meetings are being held to address concerns and educate the public on identifying and reporting drug-related crimes. Law enforcement emphasizes the importance of community involvement in maintaining a safe neighborhood.
Accredited Drug Testing offers fast, reliable employment screening services in East Foothills, CA. Trusted by employers nationwide for accurate results and exceptional service.
California DOT/Non DOT Physicals
RNR Recovery
Santa Clara Community Services
Santa Clara County Behavioral Health Services
Alcoholics Anonymous
Nar-Anon Family Groups
SAMHSA National Helpline
Recovery.org
NCADD California
CA.gov Health Services
Sara Foundation
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024