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At our 21 testing centers throughout East Kern, California, Accredited Drug Testing offers thorough screening for drugs and alcohol. From DOT to non-DOT urine tests, breath and EtG alcohol checks, even hair tests, we cater to personal, work-related, and legal inquiries. Our East Kern facilities deliver fast result services and SAMSA accredited lab analyses; same-day appointments are possible, typically a short drive from businesses or residences. Further services encompass Background Checks, Clinical and Occupational Health Testing.
Reach out at (800) 221-4291 or register via our website. It's straightforward to pick a test and select a nearby venue—whether it’s for yourself, employees, or others. You can schedule your test quickly, either by calling us or via our 24/7 online platform. With our efficient process, organizing drug tests in East Kern is simple and hassle-free.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our East Kern drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Mojave, Kern County, approximately 12% of residents have reported illicit drug use in the past month.
California City, in Kern County, saw a 15% increase in drug-related arrests from 2018 to 2019.
Tehachapi, Kern County, reported over 150 drug-related emergency room visits in 2020.
Ridgecrest in East Kern County experienced a 10% rise in opioid overdose cases in 2019.
The Kern County Sheriff's Office reported 250 drug trafficking offenses in the East Kern area in 2021.
In East Kern, nearly 20% of high school students admitted to trying marijuana at least once in 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in East Kern, CA, have been increasingly adopting comprehensive drug testing policies. This is part of efforts to ensure safety and productivity in the workplace. Many businesses collaborate with organizations such as the California Department of Industrial Relations to implement these policies.
These drug testing protocols vary among employers, but generally include pre-employment screening, random testing, and post-incident testing. Some companies also offer employee assistance programs to support workers struggling with addiction, encouraging a supportive work environment.
The government has been actively working to address the drug problem in East Kern, CA, through local and state agencies. Initiatives include increased funding for law enforcement and rehabilitation programs. Kern County Sheriff's Office has ramped up their anti-drug campaigns.
The state of California has been investing in community outreach and awareness programs to tackle substance abuse. The California Department of Health Care Services supports various treatment and prevention efforts, providing critical funding and resources to local initiatives in East Kern.
In East Kern, a significant drug bust led to the seizure of large quantities of methamphetamine. Law enforcement agencies collaborated on a months-long investigation, culminating in multiple arrests. The operation emphasized the commitment of local authorities to curb drug trafficking, enhancing community safety.
An aggressive crackdown on drug-related activities in East Kern County has led to increased patrols and surveillance. Officials are engaging with the community to report suspicious activities, aiming to dismantle larger networks. These actions have resulted in a safer environment and a reduction in drug distribution in rural areas.
Community forums in East Kern have been instrumental in raising awareness about drug abuse and prevention strategies. These events provide crucial information, fostering a proactive approach among residents to recognize and report illegal activities. This collaborative effort has empowered the community to take a stand against drug-related crime.
Accredited Drug Testing offers fast, reliable employment screening services in East Kern, CA. Trusted by employers nationwide for accurate results and exceptional service.
California DOT/Non DOT Physicals
Kern County Sheriff's Office
California Department of Health Care Services
California Department of Industrial Relations
Substance Abuse and Mental Health Services Administration
National Institute on Drug Abuse
Stop Teen Drug Use
Seekers of Serenity
Tarzana Treatment Centers
BAART Programs
Kern Behavioral Health & Recovery Services
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024