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At our 39 testing centers located around Los Gatos, CA, Accredited Drug Testing delivers a wide range of drug and alcohol testing services. We offer a variety of options including DOT and non-DOT urine drug testing, breath alcohol assessments, EtG alcohol tests, and hair drug screenings tailored for personal, employment, or legal purposes. Fast results and SAMSA certified lab analyses are available, with many Los Gatos centers conveniently close to you. Additional offerings include Occupational Health and Clinical Testing, along with Background Verification services.
Reach out to us at (800) 221-4291 or register on our website. Pick your desired test and select a location nearby—our testing services are available for you, employees, or other individuals. The scheduling process is efficient and straightforward, either by calling our team or using our 24/7 online scheduling tool. Experience the ease of planning your drug testing within Los Gatos using our simplified system.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Los Gatos drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Los Gatos, situated in Santa Clara County, reported a 15% increase in opioid overdoses over the past year.
50% of the drug-related arrests in Los Gatos last year involved individuals under the age of 30.
In Los Gatos, the prevalence of marijuana use among teens was reported to be higher than the national average.
Los Gatos, Santa Clara County, had an 8% decrease in methamphetamine-related crimes in comparison to the previous year.
Alcohol remains the most abused substance in Los Gatos, with 23% of reported substance issues involving alcohol.
A survey indicated that 7% of adults in Los Gatos, California, have used prescription drugs non-medically in the past year.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Los Gatos, CA, recognize the importance of maintaining a drug-free workplace. Many companies have instituted mandatory drug testing policies to ensure safety and productivity. These tests are often part of the hiring process and may be conducted randomly. For more information about workplace drug policies, refer to the California Department of Industrial Relations.
In addition to pre-employment screenings, Los Gatos employers may require routine testing as part of their occupational safety programs. These initiatives serve to deter substance abuse and help provide support for employees who need help.
The government of Los Gatos, CA, in cooperation with Santa Clara County, has implemented various initiatives to address the growing drug problem. This includes funding for rehabilitation centers and increased educational programs in schools to prevent drug addiction.
Local agencies such as Santa Clara County Behavioral Health Services provide resources for those struggling with substance abuse.
Los Gatos, CA, has seen its share of local drug busts and events related to drug offenses. Recently, police efforts led to a significant methamphetamine seizure, disrupting a local distribution network. These busts are part of the ongoing work by law enforcement to curb illegal drug activities.
Community events aimed at raising awareness about the dangers of drug abuse are regularly organized. These events often include workshops and seminars on addiction prevention and recovery support, highlighting efforts by both law enforcement and public health departments.
A notable collaboration between the police department and the community resulted in increased patrols in known drug hotspots, helping to reduce criminal activity associated with drug trafficking. Public initiatives play an integral role in the strategy against narcotics in Los Gatos.
Accredited Drug Testing offers fast, reliable employment screening services in Los Gatos, CA. Trusted by employers nationwide for accurate results and exceptional service.
California DOT/Non DOT Physicals
Santa Clara County Behavioral Health Services
Santa Clara County District Attorney's Office
California Department of Public Health
California Department of State Hospitals o-drug Response
SAMHSA's National Helpline
National Institute on Alcohol Abuse and Alcoholism
National Institute on Drug Abuse
CDC Drug Overdose
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024