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Accredited Drug Testing provides an extensive array of drug and alcohol testing solutions at 31 centers throughout the Northeast Marin, California region. Our services include both regulated and non-regulated urine drug screens, breath alcohol assessments, EtG alcohol tests, and hair drug screenings. Whether for personal, employer, or legal purposes, our Northeast Marin, CA centers deliver rapid results and SAMSA-certified laboratory analysis. Many testing sites are conveniently located close to your residence or workplace, offering same-day appointments. Our additional offerings encompass Occupational Health Evaluations, Clinical Diagnostics, and Background Verification.
Reach us at (800) 221-4291 or proceed with online registration. Select your required test, and choose a convenient nearby location; testing options are available for yourself, employees, or others. Arranging a test is swift and straightforward—contact our scheduling team or book your appointment online anytime. Our process, both efficient and intuitive, simplifies the organization of drug tests near Northeast Marin.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Northeast Marin drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2020, Fairfax, Marin County reported a 25% increase in opioid overdoses compared to 2019.
A 2021 study showed that 15% of high school students in San Rafael, Marin County had tried illicit drugs.
The Marin County health department reported 300 drug-related emergency visits in Mill Valley in 2020.
In 2021, Larkspur, Marin County recorded a 12% rise in drug possession arrests.
Novato, Marin County experienced a 30% decline in drug abuse treatment admissions in 2021.
In 2022, Marin City saw a 20% decrease in drug abuse-related crimes.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Northeast Marin, CA are increasingly adopting drug testing policies to ensure workplace safety and productivity. Many companies conduct pre-employment screenings and random drug tests as part of their efforts to maintain a drug-free environment. This approach is particularly prevalent in safety-sensitive industries such as construction and transportation.
The Marin Employment Connection (Marin Employment Connection) advises local businesses on best practices for implementing drug testing policies, ensuring compliance with state regulations. Employers are encouraged to provide support and access to treatment for employees who struggle with substance abuse, fostering a more supportive workplace.
The government of Northeast Marin, CA is actively working to address the rising drug abuse issues through various initiatives. Marin County offers drug education programs in schools and community centers to raise awareness among youth. Additionally, the Marin County Department of Health and Human Services (Marin HHS) provides resources and support for addiction treatment and recovery.
Local law enforcement agencies collaborate with federal partners to curb drug trafficking in the region. Programs like the Marin Prevention Network focus on reducing substance use and promoting healthier, drug-free lifestyles. Moreover, the county supports several community-based organizations that offer counseling and recovery services to combat addiction.
Recently, several significant drug busts in Northeast Marin, CA highlighted the ongoing battle against drug-related activities. In 2023, a joint operation by Marin County Sheriff's Office and the DEA led to the arrest of multiple individuals involved in a large-scale drug trafficking ring operating between Marin and neighboring counties.
Community events, such as the annual 'Marin Community Drug Forum,' bring together law enforcement, healthcare professionals, and residents to discuss strategies and challenges in addressing local drug issues. These events foster collaboration and community engagement, aiming to reduce drug abuse and promote public safety.
Accredited Drug Testing offers fast, reliable employment screening services in Northeast Marin, CA. Trusted by employers nationwide for accurate results and exceptional service.
California DOT/Non DOT Physicals
Marin HHS Substance Use Services
Partnership to End Addiction
SAMHSA
Cocaine Anonymous
California Health Care Foundation
Marin Human Services
Alcoholics Anonymous
National Alliance on Mental Illness
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024