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At our 32 testing locations around Posey, California, Accredited Drug Testing delivers a broad range of drug and alcohol testing. We accommodate both DOT and non-DOT urine tests, breath alcohol analysis, EtG alcohol detection, and hair drug tests suitable for personal, business, and legal purposes. Our Posey, CA facilities offer rapid test results and SAMSA-certified lab evaluations with the convenience of same-day service. With most sites being easily accessible from your home or workplace, additional offerings include Occupational Health Assessments, Clinical Testing, and Background Screening.
Connect with us at (800) 221-4291 or register on our website. Opt for a test and pick a convenient site—testing services are ready for you, your staff, or another person. Scheduling is quick and straightforward; reach our scheduling team or book your test online anytime. Our efficient and intuitive system enables seamless drug testing arrangements near Posey.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Posey drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Posey, Kern County, approximately 15% of high school students reported using illegal drugs in the past year.
Posey, Kern County, saw a 9% increase in drug-related arrests in the fiscal year of 2022.
In 2021, Posey in Kern County documented 12 opioid-related overdoses requiring emergency intervention.
Kern County, including Posey, reported a 7% rise in methamphetamine use over the previous two years.
In Posey, Kern County, drug misuse is notably higher among adults aged 25-34, accounting for 60% of cases.
Posey in Kern County experienced 25 drug-related hospital admissions in 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Posey, CA, are recognizing the importance of maintaining a drug-free workplace. Many businesses adopt drug testing policies as part of employee recruitment and maintenance process. Such policies are aligned with state regulations and aim to ensure safety and productivity in the workplace.
According to guidelines from the Occupational Safety and Health Administration, companies are encouraged to implement clear policies addressing drug use, including random testing and support for employees dealing with addiction. These practices help reduce drug-related incidents and create a healthier work environment.
The U.S. Department of Labor offers resources to employers in Posey, CA, to assist them in developing comprehensive drug policies. This includes training management on how to recognize drug misuse and providing recovery options for employees seeking help.
To combat drug issues in Posey, CA, both local and state governments have implemented several initiatives. Collaboration between Kern County and the local law enforcement agencies includes educational programs and support services for affected families. Efforts also involve partnerships with non-profits to provide free addiction treatment options, focusing on prevention and community awareness.
The state government supports Posey by coordinating with California Department of Health Care Services, which funds rehabilitation and prevention programs in Kern County. The introduction of better healthcare policies and outreach efforts aims to reduce the drug problem significantly. These initiatives strive to create a safer environment with less substance abuse.
Posey, CA, has experienced several significant drug-related events, shedding light on the extent of substance misuse in the area. In 2022, a major bust led by the Kern County Sheriff's Office resulted in the confiscation of over $500,000 worth of illegal substances, highlighting the scale of the drug problem.
Community events focusing on drug awareness have been organized in Posey to educate residents about the dangers and signs of drug abuse. These events often feature speakers from local law enforcement and health professionals who provide advice and resources on combatting addiction.
Recently, a coordinated effort between the Kern County law enforcement and federal agencies led to the disruption of a local drug trafficking ring. This operation underscores the importance of multi-agency collaboration in addressing the drug issues affecting Posey and its residents.
Accredited Drug Testing offers fast, reliable employment screening services in Posey, CA. Trusted by employers nationwide for accurate results and exceptional service.
California DOT/Non DOT Physicals
Rehab Center
Kern County Behavioral Health and Recovery Services
Substance Abuse and Mental Health Services Administration
Legal Action Center
National Institute on Drug Abuse - California
NARCAN® Nasal Spray
Alcoholics Anonymous
Centers for Disease Control and Prevention - Drug Overdose
Office of Environmental Health Hazard Assessment (OEHHA)
California Health & Wellness
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024