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Accredited Drug Testing provides an extensive array of drug and alcohol testing services across 33 Shafter, California area locations. Our services include DOT and non-DOT urine drug tests, breathalyzer alcohol assessments, EtG alcohol measurement, along with hair drug analyses for personal, occupational, and judicial purposes. In Shafter, CA, we assure rapid testing outcomes and SAMSA-accredited lab evaluations. Offering same-day service, many of our Shafter testing sites are conveniently situated close to residential or workplace areas. Also on offer are Occupational Health Evaluations, Clinical Diagnostics, and Background Verification services.
Dial (800) 221-4291 or go online to register. Choose your desired test and select a nearby location; testing services are accessible for yourself, employees, or any specified individual. Arranging a test is swift and straightforward—contact our scheduling team or set up your test online at any time. Our efficient and intuitive system helps you schedule drug evaluations near Shafter with ease.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Shafter drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2020, Shafter, CA in Kern County reported 10% of residents admitted to using illicit drugs at least once in the past year.
Shafter, located in Kern County, saw a 15% increase in drug-related arrests from 2019 to 2021.
Kern County's Shafter community recorded a 20% rise in opioid-related overdoses in 2022.
The city of Shafter accounted for 5% of all drug trafficking arrests in Kern County in 2021.
In 2022, Shafter in Kern County initiated 25 new cases of drug abuse treatment.
Shafter witnessed a 30% increase in methamphetamine-related incidents between 2020 and 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Shafter, CA, are increasingly implementing comprehensive drug testing policies to ensure a safe and productive work environment. Many companies adhere to federal guidelines established by the Occupational Safety and Health Administration OSHA, which advocate for regular screening of employees to deter drug misuse.
Local businesses also collaborate with employment lawyers to establish fair testing procedures aligned with California's labor laws, advocating for employees' rights while promoting workplace safety. These efforts collectively aim to reduce the incidence of work-related accidents due to substance abuse, enhancing both safety and productivity across various sectors.
In Shafter, the importance of maintaining a drug-free workplace is emphasized through mandatory training sessions on substance abuse prevention, often facilitated by local health services. The goal is to educate employees about the impact of drug use and the support available to them, aligning with the statewide mission to curb addiction at work.
The city of Shafter, CA, within Kern County, has actively engaged in governmental efforts to tackle drug problems. Local initiatives such as the Kern County Behavioral Health and Recovery Services Kern BHRS collaborate with Shafter officials to implement community outreach programs. These projects aim to provide educational resources, facilitate rehabilitation services, and promote awareness about the dangers of drug misuse.
At the state level, California's Department of Health Care Services DHCS supports the city by funding grants that expand access to drug abuse prevention and treatment facilities. These initiatives are crucial in reducing drug dependence rates and fostering a healthier community. Residents are encouraged to utilize these services to combat addiction and seek recovery.
In recent years, Shafter, CA has seen significant efforts to combat drug-related activities. Local law enforcement agencies have been proactive, launching initiatives to curtail the spread of illegal substances in the community. Collaborations with neighboring jurisdictions have proven effective, leading to numerous arrests and the confiscation of substantial quantities of narcotics.
The Shafter Police Department has focused on increasing surveillance to identify and dismantle local drug distribution networks. By leveraging technology and intelligence-sharing, officers have been able to target key figures within these operations. This strategy has been instrumental in reducing the flow of illicit drugs into the area, contributing to improved public safety.
Community involvement has also played a critical role in addressing drug issues in Shafter. Awareness programs and educational campaigns have been launched to inform residents about the dangers of drug abuse. These initiatives aim to empower citizens to report suspicious activities and foster a cooperative environment to curb drug-related crimes.
Challenges remain, but the continued efforts of law enforcement and community members in Shafter underscore a collective commitment to reducing the impact of drugs. Ongoing dialogues between stakeholders help refine strategies and ensure that resources are effectively allocated to combat the ever-evolving threats posed by drug traffickers.
Accredited Drug Testing offers fast, reliable employment screening services in Shafter, CA. Trusted by employers nationwide for accurate results and exceptional service.
California DOT/Non DOT Physicals
Partnership to End Addiction
California o-drug Use Disorder Prevention and Treatment
SAMHSA National Helpline
Kern County Behavioral Health and Recovery Services
Recovery.org California
California Department of Alcohol and Drug Programs
Sober Recovery California
Narcotics Anonymous
Betty Ford Foundation
National Health Law Program
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024