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Accredited Drug Testing provides extensive drug and alcohol testing solutions from 33 centers in the South Pasadena, California vicinity. Our services include urine drug testing (DOT and non-DOT), breathalyzer alcohol tests, EtG alcohol screening, and hair drug assessments. We cater to individuals, businesses, and legal requirements in South Pasadena, CA, offering quick result options and certified laboratory analyses by SAMSA. With convenient same-day services, most testing facilities in South Pasadena are located just a short distance from where you live or work. We also provide Occupational Health Testing, Clinical Evaluations, and Background Check services.
To schedule, call (800) 221-4291 or register online. Choose your test and the nearest location—services are available for self-testing, employees, or another person. Scheduling is quick and simple; reach out to our team or use our online platform 24/7. With our efficient and straightforward system, arranging a drug test near South Pasadena is hassle-free.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our South Pasadena drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Los Angeles County, which includes South Pasadena, opioid-related overdose deaths increased by 27% from 2019 to 2021.
South Pasadena and the surrounding Los Angeles County saw a 20% increase in drug-related emergency room visits in 2021.
In 2021, Los Angeles County reported over 2,000 drug overdose deaths, with a significant portion coming from opioids.
Youth drug use in Los Angeles County, including South Pasadena, showed a noticeable decline in 2022, with a 15% drop from the previous year.
Los Angeles County accounted for 30% of California's total drug-related arrests in 2022.
In South Pasadena, drug abuse treatment admissions increased by 10% from 2020 to 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in South Pasadena are increasingly adopting drug testing policies to maintain safety and productivity in the workplace. These policies typically involve pre-employment screenings and random testing during employment, ensuring a drug-free work environment.
Many companies adhere to the California state guidelines, which allow employers to implement drug-free workplace policies. Resources such as those from the California Department of Industrial Relations provide guidance on implementing these measures lawfully and effectively.
The government of South Pasadena actively collaborates with Los Angeles County to tackle the drug problem in the area. A significant effort is the collaboration with local law enforcement and healthcare providers to implement preventive measures. Comprehensive community programs focus on raising awareness about the dangers of drug use and promoting healthy alternatives.
Statewide initiatives like those by the California Department of Health Care Services aim to expand access to treatment services. These initiatives are part of a broader strategy to reduce substance abuse and overdose rates across California, benefiting cities like South Pasadena.
In South Pasadena, police recently uncovered a drug distribution network operating out of a local residence. The operation was the culmination of a multi-month investigation, which led to the seizure of significant quantities of narcotics and the arrest of multiple individuals involved. This bust underscores the community's ongoing efforts to combat drug-related activities and highlights the need for continued vigilance.
In another notable event, authorities conducted a raid on a South Pasadena apartment suspected of housing a drug manufacturing operation. The discovery of advanced equipment and large stockpiles of chemicals suggested the production of synthetic drugs. This incident prompted a community-wide discussion on increasing awareness and preventing such activities from taking root in the neighborhood.
South Pasadena has also seen its share of smaller-scale drug-related incidents, sparking discussions on the importance of education and outreach programs. Law enforcement has been proactive in collaborating with community groups to host workshops and seminars aimed at raising awareness about the signs of drug activity and promoting preventative measures to ensure community safety.
Accredited Drug Testing offers fast, reliable employment screening services in South Pasadena, CA. Trusted by employers nationwide for accurate results and exceptional service.
California DOT/Non DOT Physicals
Community Anti-Drug Coalitions of America (CADCA)
Substance Abuse and Mental Health Services Administration (SAMHSA)
Los Angeles County Department of Public Health
Nar-Anon Family Groups
Anxiety and Depression Association of America (ADAA)
Tarzana Treatment Centers
Safehouse Philadelphia
Shatterproof
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024