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Accredited Drug Testing delivers a wide range of drug and alcohol testing services at its 30 Castlewood, Colorado facilities. Our services include both DOT and non-DOT urine screening, breathalyzer alcohol tests, EtG alcohol assessment, and hair drug screening for personal, employment, and legal requirements. In Castlewood, CO, we offer rapid results testing with SAMSA laboratory certification, and you can expect same-day service. Most testing sites in Castlewood are conveniently located close to your residence or workplace. Additional offerings include Occupational Health Testing, Clinical Testing, and Background Checks.
Dial (800) 221-4291 or sign up online. Simply pick your desired test and find a nearby center—suitable for personal, employee, or third-party testing. Arranging a test is simple and swift. Contact our scheduling team or book online anytime. Our efficient, intuitive system enables you to arrange local drug testing in Castlewood without hassle.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Castlewood drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2021, Castlewood, CO, Arapahoe County reported a 12% increase in drug-related arrests.
Opioid overdoses in Castlewood, CO, Arapahoe County rose by 18% in 2022.
Methamphetamine was involved in 23% of drug seizures in Castlewood, CO, Arapahoe County in 2022.
Heroin-related emergency visits increased by 15% in Castlewood, CO, Arapahoe County in 2022.
The Castlewood, CO, Arapahoe County Police Department noted a 9% rise in cocaine trafficking in 2021.
In 2020, marijuana possession arrests in Castlewood, CO, Arapahoe County decreased by 5%.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Castlewood, CO, employers are increasingly implementing drug testing policies to ensure workplace safety. Many companies conduct pre-employment and random drug tests to deter substance abuse. For guidance, businesses refer to SAMHSA's workplace resources.
Local firms emphasize a drug-free environment and offer employee assistance programs for those struggling with addiction. The focus is also on rehabilitation, allowing affected employees to seek help without the fear of discrimination or punitive action.
The government of Castlewood, CO, has been proactive in addressing the city's drug problems. Local initiatives focus on prevention and education. They collaborate with organizations like Colorado Department of Human Services to provide resources and support.
Efforts to curb drug abuse in Castlewood include increased funding for law enforcement and community programs. The state of Colorado offers support through state health resources, aiming to reduce the impact of drug addiction on families.
In Castlewood, CO, local authorities recently dismantled a significant drug trafficking operation after months of investigation. The operation led to several arrests, with law enforcement officials confiscating substantial quantities of illegal substances. These developments highlight the relentless efforts of the community and law enforcement to combat drug-related issues and ensure safer neighborhoods for residents.
Public awareness campaigns have become a focal point following the recent drug bust in Castlewood. Community leaders emphasize education and prevention as essential tools in reducing the impact of drugs. Local schools and community centers have ramped up their involvement, organizing events aimed at educating citizens about the dangers of drug abuse and promoting healthy lifestyle alternatives for the youth.
The Castlewood Police Department has increased patrolling and surveillance in high-risk areas after a spike in drug-related incidents. Collaborative efforts with neighboring communities have strengthened surveillance and information-sharing techniques. This cooperative approach aims to disrupt the supply chains of illicit substances efficiently and deter potential unlawful activities in the region.
Following the recent events, Castlewood's residents have been encouraged to actively participate in neighborhood watch programs. Engaging local communities not only fosters a sense of communal responsibility but also aids in promptly identifying suspicious activities. These efforts are creating a robust network of vigilant residents committed to sustaining a drug-free environment.
Support services for those impacted by drug abuse have received increased attention as communities in Castlewood strive to address the root causes of addiction. Rehabilitation centers are working closely with local authorities to provide resources and support for individuals seeking recovery. These combined efforts underscore a comprehensive approach to tackling drug-related issues at their core.
Accredited Drug Testing offers fast, reliable employment screening services in Castlewood, CO. Trusted by employers nationwide for accurate results and exceptional service.
Colorado Crisis Services
Arapahoe County Government
Denver Public Health & Environment
Substance Abuse and Mental Health Services Administration (SAMHSA)
Colorado Behavioral Health
Boulder County Addiction Services
Colorado Dept. of Human Services
Health District of Northern Larimer County
Trillium Family Services
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This is by far the easiest way to get my lab work ordered and paid for. The phone calls are short and to the point. They don’t try to push extra sales on you and when I walk in to the clinic I simply show my donor pass and with in a matter of minutes I’m done. I will continue to use ADT in the future.
Jason Jackson - 7/19/2025
Everything was great, the staff was very polite. Thank you.
Olga Petrova - 9/19/2024
The visit here is always the best . The place is always really clean. The employees are super courteous, very polite, and professional. This is the only drug lab I like to go do my drug and alcohol test. I would like to tell them thank you so much for thier excellent performance and job
Eli Gonzalez - 1/4/2025