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At our 38 testing locations in Coral Gables, Florida, Accredited Drug Testing provides extensive drug and alcohol screening solutions. Our services include DOT and non-DOT urine tests, breath alcohol evaluations, EtG alcohol screens, and hair drug tests catering to individuals, employers, and legal requirements. In Coral Gables, FL, we specialize in quick result testing and offer SAMSA certified lab analysis. Same-day service is available, and most testing centers are conveniently located close to your residence or workplace. We also perform Occupational Health Testing, Clinical Testing, and Background Checks.
Dial (800) 221-4291 or sign up online. Select the desired test and preferred location—testing is offered for yourself, employees, or others. Scheduling a test is simple and swift; contact our scheduling team or arrange your test online anytime. Our efficient, easy-to-use system lets you set up drug testing in Coral Gables with ease.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Coral Gables drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Coral Gables, Miami-Dade County reported a 15% increase in opioid-related hospital admissions in 2022.
In 2022, 46% of drug-related arrests in Coral Gables involved methamphetamine, per Miami-Dade County records.
Coral Gables, part of Miami-Dade County, ranked 5th in Florida for cocaine-related incidents in 2022.
Miami-Dade County's Coral Gables saw a 10% rise in drug overdoses in 2022 compared to the previous year.
Alcohol-related disorder cases in Coral Gables increased by 8% in 2022, according to Miami-Dade County data.
Prescription drug misuse in Coral Gables led to 12% of the city's drug treatment admissions in 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Coral Gables implement strict drug-free workplace policies. These policies are in line with guidelines from the U.S. Department of Labor and have been integrated into many employment contracts. Random drug testing is a common practice to ensure a safe work environment.
Many companies in Coral Gables focus on rehabilitation and support over punitive measures for employees struggling with addiction. Employees are often encouraged to utilize resources provided by organizations like the SAMHSA for assistance, reflecting employers' dual approach of zero tolerance and supportive care.
Coral Gables, supported by Miami-Dade County, has initiatives to mitigate drug abuse. Statewide efforts funded by the Florida Department of Children and Families focus on prevention and treatment services. Federal assistance via the Substance Abuse and Mental Health Services Administration (SAMHSA) offers grants and support.
Local law enforcement collaborates with initiatives like the DEA to combat trafficking and distribution. Public awareness campaigns aim at youth education, with efforts to inform and prevent drug misuse in collaboration with schools and community organizations.
In Coral Gables, Florida, local law enforcement recently conducted a significant drug bust that led to the seizure of a large quantity of illegal substances. Officers collaborated with various agencies to dismantle a network suspected of distributing cocaine and marijuana throughout the Miami-Dade area. The operation, which had been under surveillance for several months, culminated in multiple arrests, disrupting the flow of drugs into the community.
The police department in Coral Gables has been proactive in addressing the rising concerns surrounding drug distribution. In another recent incident, a targeted raid on a suspected drug house resulted in the confiscation of not only drugs but also firearms and cash. This action was part of a broader initiative to tackle organized crime and improve public safety in the area, highlighting the community's commitment to reducing drug-related activities.
Community outreach has played a pivotal role in drug-related efforts in Coral Gables. Awareness programs educate residents on the dangers of drug use and the importance of reporting suspicious activities. These initiatives have strengthened ties between the police and community members, aiding law enforcement in their ongoing battle against drug-related crimes. The collaboration aims to enhance the overall quality of life, assuring residents of a safer environment.
Accredited Drug Testing offers fast, reliable employment screening services in Coral Gables, FL. Trusted by employers nationwide for accurate results and exceptional service.
Florida Department of Health - Drug Overdose
SAMHSA - National Helpline
Miami-Dade County Services
National Association of County and City Health Officials
Agape Center
Drug Rehab Coral Gables
Florida Department of Children and Families
South Miami Hospital - Addiction Treatment Center
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024