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At Accredited Drug Testing, our 23 testing centers in the Upper Keys, Florida deliver extensive drug and alcohol tests. We conduct DOT and non-DOT urine drug screenings, breathalyzer alcohol tests, EtG evaluations, and hair follicle tests for personal, employment, and legal purposes. In Upper Keys, FL, we provide both swift result tests and SAMSA certified lab assessments, with same-day services often available. Our centers are conveniently situated close to your residence or workplace. We also offer Occupational Health Evaluations, Clinical Testing, and Background Verification.
Dial (800) 221-4291 or access our online registration. Just pick your desired test and find a nearby center; tests are available for yourself, your employees, or for others. Scheduling is quick and convenient. Contact our scheduling team or arrange your test online at any time. Our efficient and intuitive system ensures hassle-free drug testing arrangements near Upper Keys.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Upper Keys drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Monroe County, 16% of high school students reported illicit drug use in 2022.
Upper Keys, Monroe County saw a 25% increase in opioid prescriptions from 2020 to 2022.
The overdose rate in Monroe County was 19.8 per 100,000 residents in 2021.
In Monroe County, there were 34 reported drug-related deaths in 2021.
Monroe County saw a 30% increase in drug-related arrests from 2019 to 2021.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Upper Keys, FL, from various industries, implement drug testing policies as part of their employee management systems. These policies are designed to ensure a safe and efficient work environment by deterring substance abuse among employees. Tests are often conducted during the hiring process and periodically during employment.
The enforcement of drug-free workplace policies aligns with state regulations from agencies such as Florida Department of Business & Professional Regulation. Employers also provide employees with access to counseling and rehabilitation programs to support any workforce dealing with addiction.
The government has been proactive in addressing drug problems in Upper Keys, FL. Efforts include increasing funding for mental health services and drug rehabilitation programs. Additionally, initiatives like the Florida Department of Health aim to reduce substance abuse through community-based education and support.
Local enforcement agencies, alongside the Monroe County Sheriff's Office, collaborate in implementing stricter drug trafficking laws and enhancing surveillance to curb drug distribution. These efforts have helped in gradually reducing the overall drug abuse rates in the region.
In recent months, the Upper Keys, FL have witnessed a series of drug busts conducted by local law enforcement agencies. The significant efforts were targeted at dismantling drug trafficking operations that operated within the area, severely affecting the local community. These actions were part of a larger initiative to increase safety and reduce drug-related crime rates in Monroe County.
One notable incident involved the arrest of several individuals allegedly involved in the distribution of illegal narcotics. The joint operation between the Monroe County Sheriff's Office and federal agencies aimed to cut off supply chains that fueled local demand. Such coordinated efforts have shown promising results in holding offenders accountable and recovering substantial amounts of contraband.
Local authorities have credited community tips and advanced surveillance techniques for their success in recent drug busts. Public cooperation and the increased presence of patrols have been instrumental in deterring drug activity within popular hotspots. Additionally, educational programs aimed at prevention and awareness continue to play a crucial role in empowering residents to be vigilant against illicit drug operations.
Accredited Drug Testing offers fast, reliable employment screening services in Upper Keys, FL. Trusted by employers nationwide for accurate results and exceptional service.
Florida Health Substance Abuse
Monroe County Government
SAMHSA National Helpline
Florida Alcohol and Drug Abuse Association
Drug Abuse Florida Keys
Nar-Anon Family Groups
Florida Center for Behavioral Health
Miami Drug Abuse Resources
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024