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At our 30 Wheeler AFB, Hawaii locations, Accredited Drug Testing delivers extensive drug and alcohol tests. Catering to DOT standards and more, our services include urine assessments, breath analysis for alcohol, EtG alcohol identification, and hair follicle drug evaluation. Residents and businesses in Wheeler AFB, HI benefit from quick testing responses and SAMSA-certified lab results, often available on the same day. Most testing centers are conveniently short distances from local homes and workplaces. We also offer Occupational Health, Clinical Tests, and Background Verification services.
Reach out at (800) 221-4291 or easily register online. Choose your preferred test along with a nearby facility—our services cover individuals, employers, and third parties. It's both quick and simple to set up a test; just contact our scheduling team or arrange online anytime. Our efficient and intuitive system ensures you can locate drug testing near Wheeler Afb with ease.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Wheeler Afb drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Wheeler AFB, located in Honolulu County, HI, reported an increase in drug-related incidents by 15% over the past year.
In 2022, 62% of drug abuse cases in Honolulu County impacted military personnel stationed at Wheeler AFB.
Fentanyl was identified in 30% of drug-related arrests in Wheeler AFB, Honolulu County, HI last year.
Cannabis remains the most abused substance in Wheeler AFB, with 45% of cases in Honolulu County, HI attributed to its use.
Military families at Wheeler AFB, Honolulu County, HI, experience a higher incidence of substance abuse than the state average.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Wheeler AFB, HI, enforce strict drug policies to maintain a safe and efficient workplace environment. Regular drug testing is mandatory, particularly for roles involving safety and security. Military guidelines dictate random testing to deter substance use among personnel.
Moreover, civilian employment on the base also adheres to these guidelines, with the aim of promoting community wellbeing. Federal guidelines from the Department of Labor support these initiatives, offering assistance in crafting and enforcing effective drug-free policies.
The government has initiated several programs in Wheeler AFB, HI, to combat drug abuse effectively. Honolulu County collaborates with local military and law enforcement to conduct awareness sessions aimed at reducing drug dependence. Support services are also provided to those affected, ensuring comprehensive care.
State and federal efforts assist the military community by funding rehabilitation programs. Agencies such as the Hawaii State Department of Health and SAMHSA actively contribute to creating a drug-free environment in Wheeler AFB, offering resources and strategic plans to address the issue.
Recent months have seen several significant drug busts in the Wheeler AFB area, highlighting ongoing issues with substance trafficking. In a joint operation, Honolulu County officials confiscated substantial quantities of methamphetamine, disrupting a major supply chain into the base.
Additionally, local awareness events are regularly held to educate the community about the dangers and legal repercussions of drug abuse. These events serve as a collaborative effort between military and civilian groups to foster a cooperative approach to tackling drug issues in Wheeler AFB.
Accredited Drug Testing offers fast, reliable employment screening services in Wheeler Afb, HI. Trusted by employers nationwide for accurate results and exceptional service.
Hawaii State Department of Health
SAMHSA National Helpline
DrugAbuse.com - Hawaii
Hana Hou magazine on Hawaii drug issues
Coalition for a Drug-Free Hawaii
HealthyPurpose.org
HPU Center for Addiction Studies
Maui County ADRC
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Time was running out before my Cdl got downgraded because of a violation I had on clearinghouse. I couldn't find an employer to send me for my return to duty test, but these guys had my test scheduled and done in the same day! They saved my cdl. Thank you again!
Michael Williams - 12/2/2024
I always have a good experience setting up company driver drug screens through ADT. I'm really happy I found them while searching online, they have made my job much easier.
Exodus Heath - 2/13/2025
I use their service for new hire and DOT employee's. Spoke with Taisha Walker this morning, and she was very helpful. She made the process smooth and seamless.
Christina Galdos - 3/9/2025