Our automated scheduling system is available 24/7. Order your test online and receive your donor/registration pass by email. Click Here
Same Day Service
Accredited Drug Testing provides a wide array of drug and alcohol screening options at our 36 testing facilities in the Matthews, Indiana vicinity. We cater to DOT and non-DOT urine analyses, breath alcohol checks, EtG alcohol assessments, and hair follicle tests to meet personal, workplace, and legal requirements. In Matthews, IN, we offer rapid test results and use SAMSA certified labs, with services available the same day. Most centers are conveniently located near your home or workplace, and we also offer Occupational Health Screenings, Clinical Testing, and Background Verification.
To schedule, call (800) 221-4291 or sign up online. Pick your test and choose a nearby center—services cater to yourself, employees, or any other individual. Our scheduling is swift and hassle-free; reach our scheduling team or book a test online around the clock. Our efficient process ensures you can easily organize drug testing near Matthews with minimal effort.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Matthews drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2022, Grant County experienced a 15% increase in drug-related arrests compared to the previous year.
Matthews, IN, reported 32 drug overdose cases in 2021, marking a 25% rise from 2020.
Opioid prescriptions in Grant County decreased by 10% between 2019 and 2021.
Approximately 8% of high school students in Matthews admitted to using illegal drugs in 2021.
Grant County recorded 5 drug-related deaths in 2022, a reduction from 9 in 2020.
Outpatient treatment facilities in Matthews saw a 12% increase in admissions for substance abuse in 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Matthews, IN, have implemented strict drug testing policies to ensure a safe working environment. Pre-employment drug testing is a common requirement across various industries, aligning with state guidelines on workplace safety. Random drug tests are also conducted to deter substance use among employees.
Businesses in Grant County collaborate with organizations like the U.S. Department of Labor to stay informed about best practices in handling drug-related issues. By maintaining clear policies, employers aim to reduce productivity losses and health risks associated with drug abuse.
The government of Grant County, including Matthews, IN, has implemented various strategies to combat drug abuse. Programs aimed at education and awareness are prevalent in local schools, providing students with information on the risks of drug use. The county collaborates with Indiana Department of Administration for resource allocation.
Law enforcement agencies in Matthews work alongside state initiatives to curb drug trafficking and distribution. Grant County also supports rehabilitation programs through partnerships with the Indiana Family and Social Services Administration. These concerted efforts aim at reducing drug availability and supporting recovery for those affected.
Grant County, including Matthews, has seen several drug-related incidents in recent years. Law enforcement agencies reported a significant drug bust in 2022 involving multiple arrests and the seizure of narcotics. This operation was the result of months of investigation into a local drug network.
Community awareness rallies and events in Matthews focus on the impact of drug abuse, seeking to educate residents on prevention and support services. Local organizations host these events in collaboration with state authorities, striving to foster a drug-free environment.
Accredited Drug Testing offers fast, reliable employment screening services in Matthews, IN. Trusted by employers nationwide for accurate results and exceptional service.
Indiana Drug Monitoring Program
Indiana Drug-Free Communities
Stay Well Health
Bradley Center
CRC Health
SAMHSA
Family Guidance Centers
Indiana Mental Health Commission
Recovery.org
Quickly find trusted local drug testing centers in Matthews, IN — fast, convenient, and reliable every time!
Quickly find a local DOT drug testing center in Matthews, IN — fast, reliable, convenient nationwide service!
DNA testing for legal and non-legal purposes including child support, and child custody around Matthews, IN.
Including specimen collector training, DER training, reasonable suspicion training and much more in Matthews, IN.v
Get fast, accurate hair drug testing at our convenient Matthews, IN locations—results you can trust, every time!
Fast, reliable alcohol testing to keep your workplace safe and compliant every single day in Matthews, IN.
Reliable nationwide drug testing services ensuring accuracy, compliance, and quick results for businesses and individuals in Matthews, IN.
Accurate 5 panel drug testing with fast, confidential results—trusted by Matthews, IN employers and individuals nationwide.
Comprehensive 10 panel drug testing with fast, reliable results—trusted for Matthews, IN workplace and personal testing needs.
Convenient on-site mobile drug testing with fast, reliable results—saving time while keeping your Matthews, IN workplace compliant.
Certified DOT physicals with quick, reliable exams to keep Matthews, IN drivers compliant and on the road with confidence.
Join our DOT consortium for hassle-free compliance, random testing management, and reliable driver safety solutions.
This is by far the easiest way to get my lab work ordered and paid for. The phone calls are short and to the point. They don’t try to push extra sales on you and when I walk in to the clinic I simply show my donor pass and with in a matter of minutes I’m done. I will continue to use ADT in the future.
Jason Jackson - 7/19/2025
Everything was great, the staff was very polite. Thank you.
Olga Petrova - 9/19/2024
The visit here is always the best . The place is always really clean. The employees are super courteous, very polite, and professional. This is the only drug lab I like to go do my drug and alcohol test. I would like to tell them thank you so much for thier excellent performance and job
Eli Gonzalez - 1/4/2025