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Accredited Drug Testing provides a full range of drug and alcohol testing services through our 36 test centers in the New Palestine, Indiana region. We conduct both DOT and non-DOT urine drug screens, breath alcohol tests, EtG alcohol screenings, and hair drug analyses for individuals, employers, and legal purposes. Our New Palestine, IN facilities offer quick results testing, with SAMSA certified lab evaluations, and same-day service is usually available. Most New Palestine drug testing centers are conveniently located close to homes or offices. We also provide Occupational Health Testing, Clinical Testing, and Background Checks.
Reach us at (800) 221-4291 or sign up online. Choose your test, pick a nearby center—testing options are open for you, employees, or others. Booking a test is Simple and Quick. Contact our scheduling team or arrange your test online anytime. Our straightforward and intuitive process lets you easily set up drug testing near New Palestine.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our New Palestine drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
New Palestine, in Hancock County, saw a 12% increase in drug-related arrests in 2021.
In 2022, Hancock County reported over 50 opioid-related overdoses.
Methamphetamine use in Hancock County rose by 8% between 2020 and 2022.
In 2021, there were 32 drug arrests per 10,000 residents in New Palestine.
Hancock County health officials reported a 15% rise in heroin use in 2021.
Prescription drug misuse accounted for 20% of substance abuse cases in Hancock County in 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Many employers in New Palestine, IN, have implemented drug testing policies to ensure a safe working environment. These policies are typically aligned with state labor regulations, and random tests may be conducted to uphold workplace standards. The Indiana Department of Labor provides guidelines on such policies; visit the Indiana Department of Labor website for more details.
Employers emphasize a drug-free workplace by integrating educational programs for staff about the risks of substance abuse. Disciplinary measures for violations are clearly communicated to employees. Various industries, from manufacturing to retail, participate in these programs. More resources are available on the SAMHSA Workplace Resources webpage.
The government in New Palestine, IN, is actively addressing the drug problem through various initiatives. The Indiana State Police is working collaboratively with local law enforcement to curb drug trafficking. Community programs for awareness and prevention are prioritized, and funding is allocated for rehabilitation centers. More information can be found on the Indiana State Police website.
The town has engaged in several educational initiatives to raise awareness about drug abuse. These efforts include partnerships with schools and community groups to prevent drug usage among youth. The Hancock County Health Department is also involved in these programs. Visit the Hancock County Health Department for details.
Recent efforts by local law enforcement have led to significant drug busts in New Palestine, IN, demonstrating the town's commitment to combating drug-related issues. A notable event in 2022 involved the seizure of a substantial amount of methamphetamine headed toward Hancock County.
Periodic sweeps and cooperation with regional task forces have been effective in reducing the influx of illegal substances. Community support plays a crucial role in these operations. Officers often collaborate with citizens in joint efforts to monitor suspicious activities.
There have also been several awareness events aimed at educating the public on the dangers of drug use. These events often involve forums and seminars with local experts, providing valuable insights into current drug trends and prevention strategies for Hancock County residents.
Accredited Drug Testing offers fast, reliable employment screening services in New Palestine, IN. Trusted by employers nationwide for accurate results and exceptional service.
Indiana Division of Mental Health and Addiction
Indiana Rural Health Association
Overdose Lifeline
Hamilton County Substance Abuse Resources
Recovery.org Indiana Resources
Hancock County Health Department
Healthcare.gov Substance Abuse Coverage
Indiana Rehab Centers
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024