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With 29 convenient locations in Southport, Indiana, Accredited Drug Testing is your go-to source for complete drug and alcohol assessments. Catering to DOT and non-DOT requirements, we perform a variety of tests including urine, breath alcohol, EtG, and hair samples for personal, workplace, or legal purposes. Our Southport, IN services feature rapid response testing and SAMSA certified lab evaluations, offering same-day results. Most sites are mere minutes from your residence or workplace. We also provide Occupational Health Testing, Clinical Testing, and Background Checks.
Reach out at (800) 221-4291 or register online with ease. Choose your desired test and the closest location—available for individuals, employees, or third parties. Our process is fast and simple, either call our team for scheduling or book online anytime, day or night. This efficient and intuitive system ensures hassle-free testing at a Southport location near you.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Southport drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Southport, Marion County, drug-related arrests increased by 15% from 2020 to 2021.
Southport, Marion County reported that 25% of its emergency room visits were drug-related in 2021.
Approximately 10% of high school students in Southport, Marion County reported using illicit drugs in 2021.
Marion County, where Southport is located, saw a 30% rise in opioid overdose deaths in 2021.
In 2021, Southport, Marion County, accounted for 5% of Indiana's total drug-related crimes.
Southport, Marion County, witnessed a 20% increase in drug abuse support group attendance in 2021.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Southport, IN are increasingly integrating drug testing policies to promote a safe workplace. Many businesses follow guidelines set by the Indiana Chamber of Commerce (indianachamber.com), which emphasize implementing pre-employment and random drug screening. These practices are essential, particularly for companies where operating heavy machinery or providing healthcare services is involved, as they contribute to reducing workplace accidents and boosting productivity.
The city’s human resource professionals recommend consulting resources from the Indiana Department of Workforce Development (in.gov/dwd/) to ensure compliance with state and federal regulations regarding employee drug testing. Employers strive to not only detect and deter drug use but also offer support mechanisms, such as employee assistance programs, for workers dealing with substance abuse. This holistic approach aims to maintain a healthy workforce and sustain long-term economic growth in Southport.
The government in Southport, IN, part of Marion County, has been actively tackling drug problems through various initiatives. The Indiana State Department of Health's website provides details on statewide programs aimed at reducing drug abuse, such as increasing access to naloxone and offering community education on the risks of drug use. In addition, city officials in Southport collaborate with the Indiana Criminal Justice Institute (in.gov/cji/) to enhance law enforcement efforts focused on cutting down drug trafficking and helping those affected by drug addiction find the right resources.
Partnerships with national organizations like Drug-Free Marion County (drugfreemarioncounty.org) also play a crucial role in addressing the drug crisis. These efforts include hosting educational workshops for parents and youth, advocating for policy changes to support recovery, and facilitating access to treatment for individuals struggling with addiction. Programs are constantly being evaluated and adjusted to respond effectively to the evolving drug dynamics in Southport and the greater Marion County region.
Southport, IN, located in Marion County, has witnessed several significant drug-related events over recent years. Law enforcement agencies, often in collaboration with the Indiana State Police (in.gov/isp/), have executed multiple drug busts aimed at curbing the distribution of illegal substances. For example, a notable operation in 2021 led to the arrest of a major drug trafficking ring, resulting in the seizure of large quantities of narcotics that were being circulated in the Southport area.
Community events focusing on drug abuse prevention have also taken center stage. Southport's local schools and community centers have hosted events like 'National Night Out', raising awareness about the dangers of drug abuse and promoting resources for those in need. These activities are crucial in dismantling drug networks and providing educational tools to help individuals resist the lure of substance abuse, significantly impacting public consciousness in Southport and the surrounding Marion County region.
Accredited Drug Testing offers fast, reliable employment screening services in Southport, IN. Trusted by employers nationwide for accurate results and exceptional service.
IDEM Environmental Health
Overdose Lifeline
Indiana Addiction Issues Coalition
Fairbanks Support & Treatment
Eskenazi Health Addiction Recovery
Substance Rehab Center Southport
Mental Health America Indiana
Indiana Division of Aging - Addiction Services
Indiana Recovery Network
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024