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With 35 testing locations around Franklin, Kansas, Accredited Drug Testing delivers extensive drug and alcohol screening services. We cater to DOT and non-DOT urine drug tests, breath alcohol exams, EtG alcohol assessments, and hair drug tests for personal, occupational, and legal purposes. Rapid results testing and SAMSA certified lab analysis are accessible in Franklin, KS, with same-day appointments, and testing centers conveniently located close to you. We also offer Occupational Health Testing, Clinical Testing, and Background Check services.
Dial (800) 221-4291 or register online easily. Select your desired test and pick a local center—testing suits personal needs, employee requirements, or others. Arranging a test is quick and simple; contact our scheduling team or make an online booking any time, day or night. Our efficient and intuitive process makes it easy to coordinate drug testing near Franklin.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Franklin drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Franklin, KS, located in Franklin County, 12% of high school students have tried drugs.
Franklin County reports a 20% increase in drug overdose cases over the past three years.
There are approximately 250 drug-related arrests annually in Franklin County, KS.
Franklin, KS witnessed a 15% rise in opioid prescription rates in the last two years.
The number of methamphetamine-related incidents in Franklin County has doubled in the past five years.
Emergency room visits due to drug abuse in Franklin County, KS, have increased by 18% recently.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Franklin, KS, have increasingly adopted stringent drug testing policies to ensure a safe and productive workplace environment. Regular drug screenings are conducted as part of the hiring process, and random tests are incorporated to maintain compliance. This approach helps to deter substance abuse within the workforce.
Companies are encouraged by the state to adopt policies in line with recommendations from the Kansas Department of Labor. Employers receive resources and training on how to effectively implement their drug testing policies and handle substance abuse issues among employees, fostering a healthier business environment.
Furthermore, many businesses in Franklin actively participate in community programs aimed at drug prevention and education, understanding that a comprehensive approach is essential in tackling the broader issue of substance abuse. They work closely with local agencies to support employees in overcoming addiction through provided resources and counseling options.
The government of Franklin, KS, has been actively engaging in measures to curb drug abuse through various programs. Notably, they have increased funding for rehabilitation centers, providing greater support and resources for individuals struggling with addiction. Additionally, they collaborate with the Kansas Department for Aging and Disability Services to implement statewide substance abuse prevention campaigns.
Efforts are also focused on educational programs in schools across Franklin County, aiming to inform young individuals about the dangers of drug abuse. The city partners with the Substance Abuse and Mental Health Services Administration to enhance community awareness. Continued government oversight and intervention play a critical role in addressing and mitigating substance abuse issues within the region.
Franklin, KS, has witnessed several significant drug-related events and busts in recent years, reflecting the ongoing challenges faced by law enforcement in tackling narcotics trafficking. Coordinated efforts between the Franklin Police Department and state agencies have led to substantial seizures of illegal substances.
For instance, a recent operation resulted in the arrest of multiple individuals involved in a methamphetamine distribution network. This collaborative effort underscores the importance of joint operations in effectively dismantling drug networks.
These activities highlight the persistent nature of drug-related crime within Franklin County and the necessity for continued vigilance and proactive measures to combat these threats effectively.
Accredited Drug Testing offers fast, reliable employment screening services in Franklin, KS. Trusted by employers nationwide for accurate results and exceptional service.
Kansas State Government
Kansas Department for Aging and Disability Services
Substance Abuse and Mental Health Services Administration
Kansas Department of Labor
National Institute on Drug Abuse
Kansas Substance Use Prevention
Franklin County Sheriff's Office
Kansas City Public Health Resources
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024