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Accredited Drug Testing delivers extensive drug and alcohol testing solutions at our 38 Grandview Plaza locations in the Kansas region. Our services include DOT and non-DOT urine drug testing, breath and EtG alcohol screenings, as well as hair drug analysis tailored for individuals, employers, and legal purposes. In Grandview Plaza, KS, we offer rapid result tests alongside SAMSA-certified lab findings, with same-day service options, ensuring that most testing sites are conveniently located within minutes from your home or workplace. We also provide Occupational Health Testing, Clinical Testing, and Background Check services.
Reach out via (800) 221-4291 or register online. You can simply choose your required test type and pick a convenient location—testing available for you, your employees, or another person. Scheduling is fast and easy through our scheduling department or with our 24/7 online service. Our efficient and straightforward approach ensures you can effortlessly arrange drug testing near Grandview Plaza.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Grandview Plaza drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2022, Grandview Plaza, Geary County reported 142 cases of drug abuse incidents.
Opioid prescriptions in Grandview Plaza, Geary County decreased by 18% from 2020 to 2023.
Methamphetamine-related arrests rose by 25% in Grandview Plaza, Geary County from 2021 to 2023.
Geary County saw a 12% increase in hospital admissions due to drug overdoses in 2022.
In 2021, 8% of high school students in Grandview Plaza, Geary County reported using illicit drugs.
Grandview Plaza, Geary County PD recorded 98 drug-related offenses in the first half of 2023.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Grandview Plaza, KS, emphasize the importance of maintaining a drug-free workplace, implementing strict drug testing policies. Mandatory screening is commonly conducted for safety-sensitive positions, and random testing programs are prevalent across several industries. These actions align with the guidelines set by the U.S. Department of Labor.
The state's emphasis on a safe work environment encourages employers to provide drug awareness training and resources to their employees. Many businesses in Grandview Plaza have established Employee Assistance Programs (EAPs) that offer support services and counseling for those struggling with substance abuse issues, further reinforcing their commitment to workforce well-being.
The government of Grandview Plaza, KS, in collaboration with Geary County, has intensified efforts to combat drug abuse through various initiatives. The establishment of community awareness programs aims to educate the public on the dangers of drug misuse. These efforts are supported by Kansas Department for Aging and Disability Services, focusing on prevention and treatment strategies.
Local authorities have also collaborated with the U.S. Department of Justice to enhance law enforcement capabilities and resources committed to tackling drug-related crimes. Continued funding for treatment centers and support for rehabilitation services have also been prioritized to provide assistance to affected individuals in Grandview Plaza, KS.
Recent drug-related events in Grandview Plaza, KS, highlight ongoing efforts to combat illegal substance distribution. In late 2022, a significant operation led by the Geary County Sheriff's Department resulted in multiple arrests of individuals involved in a drug trafficking ring.
Community-driven initiatives have also made a positive impact, such as drug take-back events held throughout the year to encourage the safe disposal of unused medications. Collaboration between local law enforcement and community groups continues to play a pivotal role in identifying and addressing drug-related activities within the region.
Accredited Drug Testing offers fast, reliable employment screening services in Grandview Plaza, KS. Trusted by employers nationwide for accurate results and exceptional service.
Kansas Prevention Collaborative
Kansas Addiction Treatment Resources
DCCCA Substance Use Disorder Services
SAFE Project Kansas
Mirror Inc. Addiction Treatment
Valley Hope of Kansas
Flint Hills Addiction Treatment Center
SAMHSA Helpline
Drug Policy Alliance
Kansas AAP on Drug Abuse
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024