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Accredited Drug Testing delivers a full range of drug and alcohol testing solutions at our 8 Horace, Kansas area facilities. We conduct both DOT and non-DOT urine drug screenings, breath alcohol analyses, EtG alcohol assessments, and hair follicle drug tests for personal, business, and legal requirements. Our services in Horace, KS include quick testing with SAMSA certified lab assessments, offering same-day service, with most locations a short distance from your home or workplace. We also provide Occupational Health Testing, Clinical Analysis, and Background Verification services.
Reach us at (800) 221-4291 or register online. Select the test you need and pick a nearby site—testing services are open for you, your staff, or another party. Whether calling our scheduling team or booking online round-the-clock, organizing your test is quick and straightforward. Our efficient system ensures easy setup of drug testing in Horace with minimal effort.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Horace drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Horace, KS, Greeley County recorded a 25% increase in drug-related offenses over the past 5 years.
Substance abuse treatment admissions in Greeley County have increased by 15% in the last decade.
Greeley County reports that opioid prescriptions per capita have decreased by 10% since 2018.
Methamphetamine-related incidents account for 40% of all drug-related cases in Horace, KS.
A survey in Greeley County suggests that 18% of residents know someone who struggles with substance abuse.
The 2022 health report indicates a 5% decrease in drug overdose deaths within Greeley County.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Horace, KS, are increasingly adopting stringent drug testing policies to ensure workplace safety and productivity. Many businesses collaborate with the Kansas Department of Labor to implement compliant and comprehensive testing procedures, including pre-employment, random, and post-accident testing. These measures help deter drug use among employees and maintain an efficient work environment.
Several companies in the region offer employee assistance programs (EAPs) to support workers struggling with substance abuse. These initiatives often include confidential counseling services and referrals to professional treatment providers. Employers can access state resources through the Kansas Department of Labor to stay updated on policy guidelines and available support services.
In recent years, the government in Horace, KS, has taken significant steps to combat drug issues in Greeley County. The Kansas Department for Aging and Disability Services collaborates with local officials to enhance treatment facilities and provide comprehensive recovery programs. The county's law enforcement agencies have intensified their surveillance and intervention protocols to curb drug trafficking and misuse.
Local authorities are partnering with state-run initiatives to promote community awareness and education campaigns aimed at preventing drug abuse. Furthermore, the Kansas Bureau of Investigation offers resources and support for combating illegal drug activities in the region. For more detailed information, visit the Kansas Department for Aging and Disability Services and Kansas Bureau of Investigation websites.
Recently, Horace, KS, has seen a series of drug-related events that have captured public attention. Local law enforcement agencies in Greeley County successfully executed a major drug bust, resulting in multiple arrests and the seizure of substantial quantities of narcotics. This operation highlighted the collaborative efforts between state and local authorities to dismantle illicit drug networks in the area.
Community events, such as drug take-back days organized by the Horace Police Department, provide residents with an opportunity to safely dispose of unused medications. These initiatives aim to prevent prescription drug misuse and raise awareness of the dangers associated with improper drug disposal. Public participation in these events has been steadily increasing, reflecting a heightened community commitment to tackling substance abuse issues.
Accredited Drug Testing offers fast, reliable employment screening services in Horace, KS. Trusted by employers nationwide for accurate results and exceptional service.
DCF Drug and Alcohol Prevention
Behavioral Health Services
Kansas Drug Card
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SAMHSA National Helpline
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KDADS BHS
Targeted Case Management
Partnership to End Addiction
U.S. Drug Enforcement Administration
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024