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Accredited Drug Testing provides a full range of drug and alcohol screening options at 32 different testing facilities in the Berwick, Maine area. Our services include both DOT and non-DOT urine drug screenings, breath alcohol evaluations, EtG alcohol assessments, and hair follicle drug examinations for personal, workplace, and legal purposes. In Berwick, ME, we offer swift results testing along with SAMSA-certified laboratory analyses. Same day service is accessible, and most drug testing centers are conveniently near your home or office. We also provide Occupational Health Testing, Clinical Testing, and Background Checks.
Dial (800) 221-4291 or register via our website. Simply pick your test and choose a nearby testing center—options are available for self, employees, or other individuals. Scheduling a test is Quick and Efficient; you can contact our scheduling team or book online anytime, day or night. Our efficient and intuitive system makes it simple to organize drug testing in Berwick without hassle.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Berwick drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Berwick, York County, saw an increase in drug-related arrests by 15% in 2022 compared to 2021.
In Berwick, York County, opioid-related overdoses accounted for 30% of emergency room visits in 2022.
York County reported that Berwick had 120 drug-related hospital admissions in the first half of 2023.
A survey in Berwick, York County, revealed that 22% of high school students had experimented with illicit drugs in 2023.
Berwick, York County, experienced a 10% decrease in drug-related fatalities between 2021 and 2022.
In 2023, Berwick's York County law enforcement confiscated over 5,000 grams of illegal substances.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Berwick, ME enforce strict drug testing policies to maintain a safe work environment. Many local businesses have partnered with the Society for Human Resource Management to stay informed about compliance and best practices for employee drug screenings.
Yankee Candle, one of the larger employers in the area, reportedly conducts random drug tests as a part of their employment policy to ensure workplace safety. They work closely with health agencies like SAMHSA for guidance on maintaining compliant drug-free workplaces.
The government in Berwick, ME has been actively working to combat drug abuse through various local and state initiatives. The York County Sheriff's Office collaborates with the Maine Drug Enforcement Agency to address drug trafficking and abuse.
Additionally, the state has implemented preventive measures through the Maine Office of Substance Abuse by promoting education and rehabilitation programs aimed at reducing substance dependency in communities like Berwick.
Recent drug-related events in Berwick, ME, have highlighted the town's ongoing battle against illegal drug activities. In July 2023, the York County Police conducted a major drug bust leading to the arrest of several individuals involved in a regional drug trafficking operation.
Community events such as the 'Berwick Against Drugs' march in partnership with local schools and civic groups aim to raise awareness and encourage community participation in the fight against substance abuse.
Local authorities in Berwick frequently organize educational workshops and community meetings to inform residents about the dangers of drug abuse and encourage safe practices within York County.
Accredited Drug Testing offers fast, reliable employment screening services in Berwick, ME. Trusted by employers nationwide for accurate results and exceptional service.
Maine Office of Substance Abuse
Maine Drug Enforcement Agency
Ready to Quit Maine
Hope Act Recover
Prevention for ME
University of Maine's Center on Aging
Maine o-drug Response
York County Government
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Time was running out before my Cdl got downgraded because of a violation I had on clearinghouse. I couldn't find an employer to send me for my return to duty test, but these guys had my test scheduled and done in the same day! They saved my cdl. Thank you again!
Michael Williams - 12/2/2024
I always have a good experience setting up company driver drug screens through ADT. I'm really happy I found them while searching online, they have made my job much easier.
Exodus Heath - 2/13/2025
I use their service for new hire and DOT employee's. Spoke with Taisha Walker this morning, and she was very helpful. She made the process smooth and seamless.
Christina Galdos - 3/9/2025