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Accredited Drug Testing provides a wide array of drug and alcohol testing solutions across 20 locations in the Frankfort, Maine region. Our services include DOT and non-DOT urine drug tests, breathalyzer alcohol tests, and EtG alcohol testing, as well as hair drug tests, suitable for personal, employment, or legal purposes. Fast result testing with SAMSA-certified lab analysis is available in Frankfort, ME, and same-day service can be offered. Most testing facilities are convenient to reach from either your residence or workplace. Our range also spans Occupational Health Testing, Clinical Testing, and Background Checks.
Contact us at (800) 221-4291 or register online. Choose your test and pick a nearby location—our services accommodate individuals, employees, or third parties. Booking a test is quick and convenient. Call our scheduling team or make arrangements online any time, day or night. Our intuitive process simplifies setting up drug testing close to Frankfort without hassle.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Frankfort drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Frankfort, located in Waldo County, ME, saw a 15% increase in opioid-related overdoses in 2021.
The town of Frankfort in Waldo County reported 78 drug-related arrests in 2022.
Emergency services in Frankfort, Waldo County responded to over 150 drug-related emergencies in 2022.
In 2021, Waldo County, which includes Frankfort, reported a 25% rise in synthetic drug use.
Frankfort has the highest rate of prescription drug misuse in Waldo County according to 2022 data.
Waldo County experienced a 10% decrease in drug overdose deaths in 2022, affecting areas like Frankfort.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Frankfort, ME, are actively implementing drug testing policies to promote a safe and healthy workplace. These policies typically include pre-employment drug screenings and random testing for current employees. Such measures aim to deter substance abuse and ensure compliance with workplace safety standards.
Local businesses often collaborate with organizations like Maine Department of Labor to ensure that their drug testing policies comply with state regulations. The support from the state aids employers in maintaining a drug-free work environment, thereby improving productivity and employee well-being.
The government of Frankfort, ME, in conjunction with state and federal agencies, has implemented various initiatives to combat drug abuse. These efforts include educational programs and outreach campaigns aimed at raising awareness on the risks of drug addiction. Collaborations with Maine Department of the Attorney General and SAMHSA provide resources for prevention and recovery support.
Moreover, Frankfort has increased funding for local law enforcement to assist in drug-related investigations and enforcement. The partnership with Maine Department of Health and Human Services enhances access to treatment services for individuals battling addiction. These measures strive to reduce the impact of the drug problem in Frankfort.
In recent years, Frankfort, ME, has witnessed several notable drug busts, reflecting the ongoing battle against narcotics in the area. Local law enforcement efforts have led to significant seizures of illicit substances, often involving collaboration with federal agencies.
These drug-related events highlight the persistent efforts of the police force in Frankfort to curb the spread of illegal drugs. Public awareness campaigns often follow such busts to educate the community on the dangers of substance abuse and encourage reporting of suspicious activities.
Accredited Drug Testing offers fast, reliable employment screening services in Frankfort, ME. Trusted by employers nationwide for accurate results and exceptional service.
Maine DHHS Substance Abuse and Mental Health Services
211 Maine
Maine Department of the Attorney General
SAMHSA National Helpline
Maine Emergency Management Agency on Drug Abuse
University of Maine - Margaret Chase Smith Policy Center
Prevention for ME
Healthy US Collaborative - Maine
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Time was running out before my Cdl got downgraded because of a violation I had on clearinghouse. I couldn't find an employer to send me for my return to duty test, but these guys had my test scheduled and done in the same day! They saved my cdl. Thank you again!
Michael Williams - 12/2/2024
I always have a good experience setting up company driver drug screens through ADT. I'm really happy I found them while searching online, they have made my job much easier.
Exodus Heath - 2/13/2025
I use their service for new hire and DOT employee's. Spoke with Taisha Walker this morning, and she was very helpful. She made the process smooth and seamless.
Christina Galdos - 3/9/2025