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Comprehensive drug and alcohol testing services are available at our 25 locations around Randolph, Maine, courtesy of Accredited Drug Testing. We conduct both DOT and non-DOT urine drug tests, as well as breath and EtG alcohol assessments, plus hair drug tests tailored for individuals, businesses, and legal circumstances. Our rapid results and SAMSA-certified lab analyses conveniently serve Randolph, ME, with most test centers just minutes away from home or work, offering same-day service. We also provide Occupational Health Testing, Clinical Testing, and Background Checks.
Dial (800) 221-4291 or register through our website. Pick your desired test and location conveniently close to you—whether it's for personal, employee, or third-party testing. The Fast and Easy scheduling process can be accessed via our scheduling team or online anytime. Our efficient and convenient platform ensures an effortless arrangement of drug tests near Randolph.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Randolph drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2022, Randolph, ME in Kennebec County reported a 15% increase in opioid overdose cases.
The Kennebec County Sheriff's Office recorded 120 drug-related arrests in Randolph, ME in 2021.
Randolph, ME has seen a 25% rise in drug-related crimes from 2020 to 2022.
Emergency medical services in Randolph, ME responded to 50 drug overdose calls in 2021.
In 2023, 40% of high school students surveyed in Kennebec County reported trying illegal drugs.
Randolph, ME ranks third in Kennebec County for opioid prescriptions filled per capita.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Randolph, ME, recognize the importance of maintaining a drug-free workplace. Many have adopted comprehensive drug testing policies that include pre-employment, random, and for-cause drug testing. Policies are in line with the SAMHSA workplace guidelines to ensure compliance with state and federal requirements.
Some local businesses provide access to employee assistance programs (EAPs) to help staff with substance abuse issues. These programs are designed to offer help and support to employees struggling with addiction while maintaining confidentiality.
Randolph employers actively participate in training programs to help supervisors recognize signs of drug abuse. This proactive approach aims to support early intervention and prevent workplace safety issues, in accordance with OSHA standards.
The government of Randolph, ME, in conjunction with Kennebec County, has implemented several programs to tackle drug abuse. These include increased funding for substance use disorder treatment facilities and enhanced community outreach initiatives. To learn more, visit the Maine Department of Health and Human Services and the Substance Abuse and Mental Health Services Administration.
Local officials have also partnered with law enforcement to reduce drug trafficking. Through increased patrols and community policing, the government aims to decrease availability and access to illegal drugs. Access additional information through the Maine State Police website.
Recent local drug busts in Randolph, ME, have demonstrated the ongoing efforts of law enforcement to crack down on illegal drug activity. A major operation in early 2023 led to the arrest of several individuals involved in a cross-county drug trafficking ring, highlighting the seriousness of the issue.
Community events aimed at raising awareness about drug abuse have been organized by local non-profits and health providers. These events focus on education and prevention, providing resources and support to those affected by addiction. Visit the Maine Public Health website for current information.
Another significant event in 2023 was the launch of a ‘Take Back Day’ in Randolph, allowing residents to safely dispose of unused prescription medication. This initiative, supported by local pharmacies and the police department, aims to reduce the risk of drug misuse in the community.
Accredited Drug Testing offers fast, reliable employment screening services in Randolph, ME. Trusted by employers nationwide for accurate results and exceptional service.
Maine Department of Health and Human Services
Substance Abuse and Mental Health Services Administration
Maine Public Health
Maine State Police
SAMHSA Workplace Guidelines
Occupational Safety and Health Administration
MaineHealth Behavioral and Mental Health
National Institute on Drug Abuse
NIDA State Page - Maine
Maine Alliance
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Time was running out before my Cdl got downgraded because of a violation I had on clearinghouse. I couldn't find an employer to send me for my return to duty test, but these guys had my test scheduled and done in the same day! They saved my cdl. Thank you again!
Michael Williams - 12/2/2024
I always have a good experience setting up company driver drug screens through ADT. I'm really happy I found them while searching online, they have made my job much easier.
Exodus Heath - 2/13/2025
I use their service for new hire and DOT employee's. Spoke with Taisha Walker this morning, and she was very helpful. She made the process smooth and seamless.
Christina Galdos - 3/9/2025