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Accredited Drug Testing delivers a complete array of drug and alcohol testing services at 37 facilities in the Harwich Port, Massachusetts vicinity. Our offerings include DOT and non-DOT urine analyses, breathalyzer alcohol checks, EtG alcohol screenings, and hair follicle assessments for various needs such as individual, corporate, and legal requirements. In Harwich Port, MA, we provide rapid testing solutions and SAMSA lab-certified evaluations, with same-day services and most venues located conveniently close to your residence or workplace. Additional offerings encompass Occupational Health Tests, Clinical Screenings, and Background Verification.
Contact us at (800) 221-4291 or register via our website. Select your preferred test and a nearby testing site—suitable for personal, employee, or other individual screening. Booking a test is quick and straightforward; phone our scheduling team or book online any time of day. Our efficient and intuitive framework lets you effortlessly organize testing near Harwich Port.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Harwich Port drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Barnstable County, where Harwich Port is located, 13.7 per 100,000 individuals experienced fatal opioid overdoses in 2020.
Harwich Port reported an 18% increase in opioid-related emergency room visits between 2019 and 2021, according to Barnstable County Health data.
In 2021, Barnstable County Health documented that 59% of drug-related fatalities were due to fentanyl in Harwich Port.
From 2018 to 2020, Harwich Port saw a 25% decrease in drug arrests, as reported by the Barnstable County Sheriff's office.
A 2021 report indicated that 8% of high school students in Barnstable County admitted to using prescription drugs without a doctor's order.
The Barnstable County Opioid Task Force reported that there were over 200 Narcan deployments in Harwich Port in 2020.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Harwich Port take drug abuse seriously and frequently implement drug testing policies as part of their hiring processes. These policies are often compliant with state and federal regulations, ensuring a safe workplace environment. The Massachusetts Department of Labor Standards offers guidance for businesses implementing these policies. Visit their website here.
Many local employers partner with drug testing providers to carry out pre-employment and random drug tests. These tests are crucial in sectors like healthcare and education, where sober work practices are vital. The emphasis is on creating workplaces that promote health and safety, contributing to lower drug use rates.
The government of Harwich Port, in collaboration with Barnstable County, is implementing comprehensive strategies to combat drug problems. The Barnstable County Regional Substance Use Council focuses on prevention, treatment, and recovery support efforts. The council's initiatives include community education and partnerships with local organizations. For more information, visit the Barnstable County Department of Human Services.
At the state level, Massachusetts has several programs aimed at reducing drug abuse, including the Massachusetts Opioid Abuse Prevention Collaborative (MOAPC). This program provides funding and support to municipalities for substance abuse prevention. Learn more through the Executive Office of Health and Human Services.
In recent years, Harwich Port law enforcement has increased efforts to curb drug-related crime, leading to several successful drug busts. In 2022, a major operation led to the arrest of several individuals involved in a regional drug trafficking ring. This bust resulted in the seizure of significant quantities of heroin and methamphetamine.
Local task forces routinely collaborate with state and federal agencies to identify and disrupt drug networks operating within Barnstable County. These operations highlight the ongoing commitment to keeping the community safe and drug-free. Frequent public forums are also held to keep the community informed and involved in local efforts.
Accredited Drug Testing offers fast, reliable employment screening services in Harwich Port, MA. Trusted by employers nationwide for accurate results and exceptional service.
Massachusetts DOT/Non DOT Physicals
Massachusetts Substance Use Helpline
Gosnold Behavioral Health Centers
Duffy Health Center
High Point Treatment Center
Fairwinds, Nantucket’s Counseling Center
Health Imperatives
Behavioral Health Community Services
Cape Cod Healthcare
Lahey Health Behavioral Services
Steppingstone Incorporated
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024