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Accredited Drug Testing delivers extensive drug and alcohol screening services at our 33 testing centers around Lakeville, Massachusetts. Our offerings include both DOT and non-DOT urine tests, breathalyzer alcohol tests, EtG tests, and hair drug assessments for individuals, employers, and legal purposes. Rapid result tests and SAMSA certified laboratory analyses are accessible with same-day service typically available. Most centers in Lakeville are conveniently located close to your home or workplace. We also provide occupational health assessments, clinical testing, and background verification services.
Dial (800) 221-4291 or register on our website. Pick your desired test and choose one of the nearby centers—testing is available for personal use, employee screening, or for another person. Our swift and simple process allows you to schedule a drug test near Lakeville effortlessly, either by contacting our scheduling team or booking online around-the-clock.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Lakeville drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2021, Lakeville, MA, part of Plymouth County, reported a 5% increase in opioid-related overdoses.
Overdoses in Lakeville, MA represented 14% of all incidents in Plymouth County in 2022.
In 2022, Plymouth County saw a 12% rise in drug-related emergency calls from Lakeville, MA.
Lakeville's drug-related crime rate rose by 7% in 2022 according to Plymouth County data.
The Massachusetts Department of Public Health reported a 6% increase in substance abuse cases in Lakeville for 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Lakeville, MA, adhere to strict drug testing policies to ensure a safe and productive work environment. Many companies follow guidelines set by the Occupational Safety and Health Administration (OSHA) and state regulations, requiring pre-employment and random drug testing.
The focus of these policies is not only on maintaining safety but also on providing assistance for employees struggling with substance abuse. Employers often offer Employee Assistance Programs (EAPs) in collaboration with local health agencies to support workers in need of help, while maintaining compliance with Massachusetts labor laws.
The government in Lakeville, MA, located within Plymouth County, has implemented various initiatives to combat drug abuse. Collaborating with the Massachusetts Department of Public Health, local authorities focus on education and rehabilitation programs to curb substance abuse.
Lakeville's local government also partners with county-wide task forces to address opioid abuse specifically. Initiatives include increasing the availability of naloxone and supporting the Plymouth County Outreach program, which provides rapid response to overdoses and connections to recovery resources.
Recent months have seen an increase in local drug busts in Lakeville, MA. Authorities have intensified efforts to combat the distribution and use of illicit substances. Several operations have been successful in uncovering networks involved in narcotics trafficking, leading to multiple arrests and seizures of significant quantities of drugs.
In a notable event, Lakeville police collaborated with neighboring departments to dismantle a regional drug ring. This operation resulted in the confiscation of not only drugs but also weapons and cash, demonstrating the severity of the issue. The crackdown highlights the ongoing challenges faced by law enforcement in addressing drug-related crimes in the region.
Community awareness initiatives are also on the rise in Lakeville, as local organizations work alongside law enforcement. These programs aim to educate the youth and community members about the dangers of drug abuse. Such efforts are vital in reducing demand and preventing the spread of illicit activities within the town.
Despite the challenges, Lakeville continues to make progress in its fight against drugs. The commitment of the local police force, combined with community support and resources from state agencies, is critical to maintaining public safety and reducing the impact of drug-related issues in the area.
Accredited Drug Testing offers fast, reliable employment screening services in Lakeville, MA. Trusted by employers nationwide for accurate results and exceptional service.
Massachusetts DOT/Non DOT Physicals
Department of Public Health
Plymouth County Outreach
Hazelden Betty Ford in Plymouth
Gándara Center
Southcoast Behavioral Health
Health Imperatives
Bay Cove Human Services
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024