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Accredited Drug Testing brings full-scale drug and alcohol assessment services to our 30 centers in the Mashpee, Massachusetts vicinity. We cater to DOT and non-DOT urine analysis, breathalyzer tests, EtG alcohol screening, and hair follicle drug tests for private, corporate, and judicial purposes. Located conveniently, most Mashpee test sites are only minutes away from your residence or workplace, offering rapid result options and SAMSA-certified laboratory evaluations. We also provide Occupational Health Screening, Clinical Testing, and thorough Background Verifications.
Reach out via (800) 221-4291 or sign up online. Simply pick your preferred test and select a center nearby—services are available for personal, corporate, or third-party testing. Test scheduling is swift and hassle-free; contact our scheduling team or set up your test round-the-clock online. Our efficient, intuitive process makes organizing a drug test around Mashpee a breeze.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Mashpee drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Mashpee, located in Barnstable County, MA, reported a rise in opioid-related overdoses by 15% in 2022.
In 2021, 18% of all drug-related hospital admissions in Barnstable County, including Mashpee, were due to heroin abuse.
Mashpee observed a 10% increase in substance abuse treatment enrollment in 2022, reflecting county-wide trends.
Barnstable County, including Mashpee, saw a 12% decrease in drug-related crime rates following community policing efforts in 2023.
The prevalence of fentanyl in drug seizures in Mashpee, Barnstable County, rose by 20% from 2021 to 2023.
Mashpee County reported 25 cases of methamphetamine-related incidents in 2022, marking a slight increase from 2021.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Many employers in Mashpee, MA, have adopted strict drug testing policies to maintain a safe and productive workplace. This is in alignment with state regulations as outlined by the Massachusetts Department of Industrial Accidents.
Additionally, Mashpee businesses often collaborate with local health services to provide employees with access to drug education and support resources. These efforts aim to prevent substance abuse and promote health and well-being within the workforce.
The Mashpee government, along with Barnstable County, has implemented several initiatives to combat drug issues in the region. Efforts include increased funding for the Massachusetts Department of Public Health to expand treatment facilities and services.
Collaboration with law enforcement and community organizations is a priority in Mashpee. Programs such as the Cape and Islands District Attorney's Office aim to reduce drug-related crimes through prevention and education. These partnerships are crucial in curbing the drug crisis in Barnstable County.
In recent months, Mashpee, MA, has witnessed a significant increase in local drug busts as law enforcement intensifies efforts to tackle the opioid crisis. Several high-profile operations have resulted in the seizure of substantial amounts of narcotics, including fentanyl and heroin. These successful raids have been the result of coordinated efforts between local police and federal agencies.
The community of Mashpee has been actively involved in supporting law enforcement initiatives aimed at curbing drug-related activities. Neighborhood watch programs and anonymous tip lines have played a crucial role in gathering intelligence that leads to arrests. Educational workshops are also being organized to inform residents about the dangers of drug abuse and how to recognize its signs.
One notable event was the recent arrest of a suspected local drug ring leader who had been operating in the Mashpee area for over a year. The arrest followed extensive surveillance operations and undercover work. This operation not only disrupted the supply chain of narcotics in the region but also shed light on the sophisticated networks being used by traffickers.
Despite these successes, law enforcement agencies in Mashpee continue to face challenges, as traffickers adapt their methods to evade detection. To combat this, increased funding has been allocated to equip local police with the latest technology and resources needed to stay ahead. Continuous training sessions ensure officers are prepared for the evolving landscape of drug crimes.
Accredited Drug Testing offers fast, reliable employment screening services in Mashpee, MA. Trusted by employers nationwide for accurate results and exceptional service.
Massachusetts DOT/Non DOT Physicals
Hope House Mashpee
Gosnold
Massachusetts Department of Public Health
North Atlantic ATC
BSAS Helpline
Cape Cod Healthcare
BAMSI
Aids Action Committee
Health Imperatives
Recovery.org
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024