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Accredited Drug Testing provides extensive drug and alcohol testing services throughout the North Seekonk, Massachusetts area at 40 locations. Our offerings include both DOT and non-DOT urine drug tests, breathalyzer tests, EtG alcohol testing, as well as hair follicle drug testing for different purposes, such as individual, employer-related, and legal. We ensure quick access to testing results in North Seekonk, MA, with SAMSA approved laboratory evaluations, and most of our testing sites are conveniently located close to residential and business areas. We also offer additional services like Occupational Health Testing, Clinical Testing, and Background Checks.
You can reach us at (800) 221-4291 or sign up on our website. Pick your desired test and find a nearby center—tests are available for personal use, employee screenings, or other individuals. Arranging a test is fast and straightforward; our scheduling team can assist, or you can manage appointments online at any time. Our efficient and intuitive system facilitates easy organization of drug tests in North Seekonk.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our North Seekonk drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
North Seekonk in Bristol County reports a steady rise in opioid-related incidents over the past five years.
Bristol County, which includes North Seekonk, has seen a 10% increase in heroin overdoses since 2019.
Emergency room visits due to drug overdoses in North Seekonk have increased by 15% over the last four years.
Prescription drug abuse accounts for nearly 25% of all drug-related incidents reported in North Seekonk, Bristol County.
Bristol County's North Seekonk has a higher-than-average rate of drug-related arrests compared to other counties in Massachusetts.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in North Seekonk, MA have implemented diverse drug testing policies to ensure a safe and productive work environment. Many companies explore pre-employment drug testing and conduct random checks to discourage substance abuse. These practices are governed by state regulations and guidelines provided by entities like the Massachusetts Office of the Attorney General.
To promote fair practices, employers often collaborate with legal experts and utilize resources from organizations such as the Massachusetts Office of the Attorney General. This ensures drug policies are in line with state labor laws and respect individual rights.
The government of North Seekonk, MA, in Bristol County, has implemented several measures to combat drug abuse. Community-based programs focusing on prevention and education have been established to address this issue. Efforts have also included collaboration with state agencies and organizations to enhance treatment and recovery options for citizens.
Additionally, the state government is actively involved in various initiatives to reduce substance abuse. The Massachusetts Department of Public Health offers extensive resources and support. For more information, visit the Massachusetts Department of Public Health.
Recent local drug busts in North Seekonk, MA have highlighted the ongoing efforts of law enforcement to combat drug-related crimes. A significant operation led to multiple arrests and seizures of illegal substances. These events are part of a coordinated strategy involving local and federal agencies to disrupt drug trafficking networks.
Community involvement is crucial in addressing these issues. There have been several community meetings and outreach programs aimed at increasing awareness and reporting suspicious activities. Both local authorities and community organizations work together to tackle the persistent challenges of drug-related crime.
Accredited Drug Testing offers fast, reliable employment screening services in North Seekonk, MA. Trusted by employers nationwide for accurate results and exceptional service.
Massachusetts DOT/Non DOT Physicals
HelpLine MA
Bureau of Substance Addiction Services
Massachusetts Department of Public Health
AdCare Hospital
Harrington Hospital Substance Use Services
Learn to Cope
Lahey Health Behavioral Services
SSTAR
Bay Cove Human Services
Health Imperatives Behavioral Health
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024