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At our 38 locations throughout Highland, Minnesota, Accredited Drug Testing delivers broad-spectrum drug and alcohol screening services. Our selection of tests includes DOT and non-DOT urine drug tests, breath alcohol testing, EtG alcohol assessments, as well as hair drug testing catered to individuals, businesses, and legal requirements. Solutions such as rapid results and SAMHA-certified lab analyses are readily accessible, often with same-day appointments. Many Highland venues are conveniently close to residential and office areas. Moreover, we provide Occupational Health Testing, Comprehensive Clinical Testing, and Background Verification.
To set up your test, either contact us at (800) 221-4291 or visit our website for online registration. Choose your test type and the most convenient location for you, whether for personal or employment purposes or for someone else. With 24/7 online scheduling or a quick call to our department, arranging a test is swift and straightforward, enabling easy access to drug testing resources in the Highland vicinity.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Highland drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2022, Highland, MN saw a 15% increase in opioid-related hospital admissions, according to Ramsey County Public Health.
Ramsey County reported that 25% of arrests in Highland, MN in 2023 were drug-related.
The Minnesota Department of Health cited a 10% rise in drug dependency cases in Highland, MN in 2021.
Highland, MN schools observed a 8% uptick in student suspension rates tied to substance abuse in 2022.
In 2022, the local police in Highland, MN reported seizing over 100 kilos of illegal drugs.
Public surveys in 2023 indicated that 40% of Highland, MN residents perceive drug use as the top community issue.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Highland, MN are increasingly adopting drug testing policies to ensure a safe workplace. Many organizations collaborate with state and local entities to implement compliant testing processes. Information on regulations can be accessed here.
These policies not only focus on ensuring workplace safety but also provide support for employees struggling with substance abuse. Companies often offer access to counseling services as part of their employee assistance programs.
Businesses are mindful of privacy concerns and aim to balance safety with employee rights. The handling of drug testing results follows strict confidentiality protocols as mandated by state laws.
The government of Highland, MN has implemented several initiatives to address the drug problem. These initiatives include collaborations with the Ramsey County Sheriff's Office to enhance law enforcement efforts and community outreach programs. Ramsey County Sheriff's Office
Additionally, the city has partnered with state-level organizations to improve substance abuse treatment and prevention. The Minnesota Department of Human Services has increased funding for programs aimed at reducing drug dependency. More details can be found here.
Highland, MN has seen several major drug busts in recent years, highlighting ongoing efforts to combat illegal drug activity. In 2023, local law enforcement seized a significant quantity of heroin, leading to multiple arrests in collaboration with the DEA.
The annual 'National Night Out' event in Highland also focuses on raising awareness about drug problems. It combines community building with educational initiatives to inform residents about the dangers of drug abuse and prevention tips.
Engagement in these events demonstrates the community's proactive stance against drug-related issues. Law enforcement encourages citizen participation, fostering a partnership between the police and local community members.
Accredited Drug Testing offers fast, reliable employment screening services in Highland, MN. Trusted by employers nationwide for accurate results and exceptional service.
Minnesota DOT/Non DOT Physicals
Minnesota Recovery
Hazelden Betty Ford Foundation
Ramsey County Public Health
Lifeworks Recovery
National Jewish Health Minnesota Centers
Minnesota Department of Human Services
MPR News on Highland's o-drug Crisis
Drug Helpline Minnesota
MentalHealth.gov Minnesota
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024