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Accredited Drug Testing provides a wide range of alcohol and drug testing services through our 38 locations around Bourbon, Missouri. We cater to DOT and non-DOT requirements with urine drug tests, breath and EtG alcohol tests, and hair drug screenings for various purposes, such as personal, employment, or legal compliance. In the Bourbon region, we offer prompt testing results and SAMSA certified lab reviews, with same-day services typically available within close proximity to your residence or workplace. Other services include Occupational Health Testing, Clinical Analysis, and Background Verification.
Dial (800) 221-4291 or register online to get started. Simply pick your desired test and select a convenient location—testing can be scheduled for yourself, employees, or someone else. Our process is Quick and Convenient, with the option to call our scheduling team or utilize our 24/7 online booking system. Enjoy a smooth, straightforward experience when arranging drug testing near Bourbon.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Bourbon drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2022, Bourbon, located in Crawford County, MO, saw a 13% increase in opioid-related overdose deaths.
Methamphetamine arrests in Bourbon, Crawford County, accounted for 40% of all drug-related arrests in 2021.
A 2020 survey revealed that 15% of Bourbon high school students reported using illicit drugs in the past year.
In Crawford County, alcohol use disorder accounted for 25% of admissions to rehabilitation facilities in 2021.
Prescription drug misuse led to 30 hospitalizations in Bourbon, MO, during the year 2021.
The Crawford County Sheriff's Office reported seizing 3,000 grams of illegal substances in Bourbon during 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Bourbon, MO, are increasingly adopting stringent drug testing policies to ensure workplace safety and productivity. The Occupational Safety and Health Administration provides guidelines for establishing drug-free workplace policies. Many local businesses have leveraged these resources to incorporate random drug testing and substance abuse support groups for employees.
Furthermore, local industrial firms often collaborate with the Centers for Disease Control and Prevention to address the pervasiveness of drug abuse across different employment sectors. By conducting regular workshops and seminars, companies aim to educate employees about the dangers of drug use, thereby fostering a healthier work environment.
The city of Bourbon, along with Crawford County, has been working on combating drug issues by launching community-focused initiatives. These efforts include partnerships with the Missouri Department of Mental Health to provide better access to addiction treatment services. Additionally, the fledgling "Bourbon Health Coalition" has been tasked with community outreach programs to educate locals on substance abuse risks.
The state government has also set up a dedicated hotline in collaboration with the Department of Social Services for confidential reporting of drug-related issues. This helpline aims to connect individuals with anonymous resources for immediate support. Furthermore, regular meetings are held with law enforcement to assess the effectiveness of current policies and adjust strategies accordingly.
Recently, a significant drug bust in Bourbon, Crawford County, led to the seizure of illegal substances valued at $200,000. The operation, conducted by the Crawford County Sheriff's Department, was a result of a month-long investigation aimed at dismantling a local drug trafficking ring. Such efforts underscore ongoing attempts to reduce drug-related criminal activities in the area.
The community has also seen various drug awareness events aimed at prevention. Annual events like the "Bourbon Recovery Walk" sponsored by local non-profits, including Rise Above It Family Outreach, are organized to showcase solidarity against drug abuse. These events provide platforms for people affected by substance abuse to share their stories and encourage others towards rehabilitation.
Accredited Drug Testing offers fast, reliable employment screening services in Bourbon, MO. Trusted by employers nationwide for accurate results and exceptional service.
Missouri Department of Mental Health
Missouri Drug Rehabs
St. Louis County, Substance Use Treatment
Substance Abuse and Mental Health Services Administration
Crawford County Drug Council
Missouri Rehab Centers
Gateway Foundation, Missouri
Hazelden Betty Ford, Missouri
Missouri Association of Drug Policy and Prevention Professionals
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Time was running out before my Cdl got downgraded because of a violation I had on clearinghouse. I couldn't find an employer to send me for my return to duty test, but these guys had my test scheduled and done in the same day! They saved my cdl. Thank you again!
Michael Williams - 12/2/2024
I always have a good experience setting up company driver drug screens through ADT. I'm really happy I found them while searching online, they have made my job much easier.
Exodus Heath - 2/13/2025
I use their service for new hire and DOT employee's. Spoke with Taisha Walker this morning, and she was very helpful. She made the process smooth and seamless.
Christina Galdos - 3/9/2025