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Accredited Drug Testing provides all-inclusive drug and alcohol testing services through 30 locations around Fair Play, Missouri. We cater to DOT and non-DOT urine screenings, breath analysis, EtG alcohol evaluations, and hair follicle drug tests suitable for personal, corporate, and legal purposes. With our Fair Play, MO centers, we ensure prompt result delivery and SAMSA certified lab processing. Same-day service is usually possible, with most sites conveniently located close to your residence or workplace. We also offer supplementary Occupational Health Testing, Clinical Analysis, and Background Verification.
Dial (800) 221-4291 or register via our website. Choose the necessary test and find the closest center—testing services extend to yourself, staff, or others. Arranging an appointment is swift and uncomplicated; contact our scheduling team or reserve online at any hour. Our efficient and intuitive system simplifies organizing drug tests near Fair Play.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Fair Play drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Polk County, including Fair Play, MO, saw a 10% increase in drug-related arrests from 2021 to 2022.
In Fair Play, MO, opioid overdoses accounted for 38% of emergency calls in 2022.
Fair Play, MO recorded a 15% rise in youth drug-related offenses in 2022, according to Polk County data.
Polk County reported that methamphetamine was involved in over 50% of drug seizures in 2022.
The annual report from Polk County Sheriff indicated a 20% increase in drug rehabilitation enrollments in Fair Play, MO during 2022.
In Fair Play, MO, 2022 data shows a 5% decrease in drug-related deaths compared to 2021, based on Polk County health reports.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Fair Play, MO, are adopting stringent drug testing policies to ensure a safe and productive workplace. Many local businesses are following guidelines set by the U.S. Department of Labor, which encourage regular drug screenings and clear substance abuse policies. This aligns with a broader trend observed throughout Polk County, fostering safer work environments.
State programs provide employers with resources to develop comprehensive drug policies. The Missouri Department of Labor offers guidance on implementing effective drug-free workplace programs. In Fair Play, local companies are not only focused on compliance but also on supporting employees seeking help, often partnering with local rehabilitation centers.
Many businesses in Fair Play recognize the benefits of maintaining a drug-free workplace, including reduced insurance costs and improved employee morale. As they continue to collaborate with state and local agencies, employers are enhancing their capabilities to prevent and address workplace substance abuse issues effectively, ensuring their contribution to the fight against drug addiction in the community.
Fair Play, MO has been actively engaging in several government-led initiatives to curb drug abuse, thanks to efforts by local and state agencies. The Missouri Department of Health has implemented statewide programs designed to boost awareness and provide education on the dangers of drug abuse. Additionally, federal task forces often collaborate with Polk County law enforcement to combat drug trafficking.
Locally, Fair Play's community leaders have organized town hall meetings and workshops aimed at educating residents on substance abuse prevention. These events are often coordinated with the assistance of the Missouri Department of Social Services, providing resources and support to those impacted by addiction. Grants from state and federal agencies help fund these initiatives, further reinforcing the community's commitment to tackling drug problems effectively.
Fair Play, MO, has been the focal point of several drug enforcement operations in recent years. Notably, an early 2022 operation conducted by the Polk County Sheriff's Office led to the arrest of multiple individuals involved in methamphetamine distribution. This operation was part of a larger effort that also included collaboration with state and federal agents.
Community-led initiatives have supported law enforcement efforts, with local residents coming together for 'Community Clean-Up Days.' These events are designed to raise awareness and deter drug-related activities by promoting community cohesion and vigilance. Local policing agencies report that such community engagement is pivotal in reducing drug-related crimes.
More recently, Fair Play hosted a 'Drug-Free Fair,' which saw participation from several hundred residents. The event focused on providing education and resources to the community. Law enforcement and health professionals spoke about the importance of early intervention and prevention in fighting drug problems, complementing the ongoing efforts to combat substance abuse in the region.
Accredited Drug Testing offers fast, reliable employment screening services in Fair Play, MO. Trusted by employers nationwide for accurate results and exceptional service.
Department of Mental Health - MO
Substance Abuse and Mental Health Services Administration
First Call Communications Center - Missouri
Missouri Sheriffs' Association (MSA)
Missouri o-drug-Heroin Overdose Prevention and Education Project
Alcohol Rehab Help - Missouri
Footprints to Freedom
Burrell Behavioral Health
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Time was running out before my Cdl got downgraded because of a violation I had on clearinghouse. I couldn't find an employer to send me for my return to duty test, but these guys had my test scheduled and done in the same day! They saved my cdl. Thank you again!
Michael Williams - 12/2/2024
I always have a good experience setting up company driver drug screens through ADT. I'm really happy I found them while searching online, they have made my job much easier.
Exodus Heath - 2/13/2025
I use their service for new hire and DOT employee's. Spoke with Taisha Walker this morning, and she was very helpful. She made the process smooth and seamless.
Christina Galdos - 3/9/2025