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Accredited Drug Testing delivers a full range of drug and alcohol testing options at 24 different centers in the Lakeland, Missouri region. Our services include DOT and non-DOT urine drug screens, breath alcohol assessments, EtG alcohol tests, and hair drug evaluations catering to individual, corporate, and legal requirements. Rapid result testing and analysis by SAMSA certified labs are offered, and same-day appointments are possible at many Lakeland sites, which are conveniently located near homes or offices. Additionally, we provide Occupational Health Assessments, Clinical Diagnostics, and Background Verification Services.
Dial (800) 221-4291 or sign up via our website. Pick the test type, choose a nearby facility, and you're set—testing is accessible for oneself, employees, or any specified person. Setting up a test is efficient and straightforward; contact our scheduling team or arrange your test online anytime. Our efficient, easy-to-navigate system ensures you can book drug tests close to Lakeland with minimal effort.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Lakeland drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2022, Lakeland, MO, located in Polk County, recorded a 15% increase in drug overdose cases compared to 2021.
Polk County reported that in 2023, opioids accounted for over 60% of drug-related hospital admissions.
In 2022, 25% of high school students in Lakeland, MO, admitted to using illicit drugs at least once.
The Polk County Sheriff's Department seized over 200 kilograms of methamphetamine in 2023.
In 2022, there was a 20% rise in drug-related crimes in Lakeland, MO, compared to the previous year.
Lakeland, MO, saw a 10% decrease in drug-related deaths in 2023 due to effective interventions.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Lakeland, MO, are increasingly implementing strict drug testing policies to ensure a safe workplace environment. Many local companies, in collaboration with the Missouri Department of Labor, are adopting random drug testing and pre-employment screenings.
These policies aim to deter drug use among employees and maintain high productivity levels. The approach is part of a broader trend within Polk County to address substance abuse issues proactively, ensuring that the workforce in Lakeland remains healthy and efficient.
Furthermore, businesses often collaborate with local health authorities to provide counseling and rehabilitation programs for employees struggling with drug addiction, thereby fostering a supportive and productive work environment.
The government of Lakeland, MO, has implemented various strategies to combat drug abuse in the area. These efforts include collaboration with state programs Missouri Department of Mental Health to provide resources and support to those affected by drug addiction. Additionally, local initiatives focus on raising awareness and prevention.
Polk County also participates in federal grants such as the Drug-Free Communities Support Program, enhancing the capabilities of local agencies and community-based organizations. The city's involvement in these programs demonstrates a commitment to reducing drug misuse and promoting public health in Lakeland.
Lakeland, MO, has witnessed several significant drug busts and events that have impacted the community. In early 2023, a major operation led by the Polk County Sheriff's Office resulted in the arrest of multiple individuals involved in a methamphetamine distribution ring.
The seizure included significant quantities of drugs and cash, emphasizing local law enforcement's ongoing efforts to curtail illegal drug activities. These events highlight the proactive measures taken by authorities to combat the drug problem in Lakeland.
Additionally, annual events such as community drug take-back days focus on raising awareness and providing residents a safe way to dispose of unused prescription medications, further contributing to the city's ongoing battle against drug abuse.
Accredited Drug Testing offers fast, reliable employment screening services in Lakeland, MO. Trusted by employers nationwide for accurate results and exceptional service.
Missouri Department of Mental Health - Alcohol and Drug Abuse
Drug Rehab Missouri
SAMHSA National Helpline
Missouri Partnership
Missouri Heroes
Narcotics.com - Missouri Rehab Centers
Recovery.com Missouri
Treatment-Centers.net Missouri Directory
National Drug Abuse Hotline
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Time was running out before my Cdl got downgraded because of a violation I had on clearinghouse. I couldn't find an employer to send me for my return to duty test, but these guys had my test scheduled and done in the same day! They saved my cdl. Thank you again!
Michael Williams - 12/2/2024
I always have a good experience setting up company driver drug screens through ADT. I'm really happy I found them while searching online, they have made my job much easier.
Exodus Heath - 2/13/2025
I use their service for new hire and DOT employee's. Spoke with Taisha Walker this morning, and she was very helpful. She made the process smooth and seamless.
Christina Galdos - 3/9/2025