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At Accredited Drug Testing, we provide top-notch drug and alcohol testing services, conveniently conducted at our 26 testing centers in the The Landing, Missouri vicinity. Our offerings include both DOT and non-DOT urine tests, breathalyzer evaluations, EtG alcohol screenings, and hair follicle drug assessments for various purposes such as personal, occupational, and legal requirements. Testing at The Landing, MO can deliver prompt results and certified lab analysis by SAMSA, with many locations just a short distance from your home or workplace. We also provide Occupational Health Tests, Clinical Analyses, and Background Checks.
Reach out to us at (800) 221-4291 or register online instantly. Simply pick your desired test and opt for a convenient location—testing services are accessible for self, employees, or other parties. Scheduling is quick and straightforward—contact our scheduling team or arrange your test online at any time. With our efficient and easy-to-use process, organizing drug tests near The Landing becomes seamless.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our The Landing drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2022, The Landing, MO recorded over 150 drug-related arrests, ranking high within Warren County.
A 2021 survey indicated that approximately 12% of adults in The Landing, MO, Warren County, used illicit drugs.
Warren County, home to The Landing, reported a 24% increase in drug overdose deaths in 2021 compared to the previous year.
The Landing saw a 15% rise in opioid prescriptions per capita in 2020-2021, according to Warren County health data.
Methamphetamine-related incidents in The Landing, MO increased by 18% in 2022, per Warren County police reports.
In 2022, drug-related emergency room visits in The Landing, Warren County, rose by 20% compared to 2021.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in The Landing, MO, are increasingly adopting strict drug testing policies to ensure a safe and productive workplace. These measures often include pre-employment screenings and random drug tests for current employees.
In line with state regulations, some local companies integrate comprehensive employee assistance programs to support those struggling with substance abuse. The Missouri Department of Labor provides resources for employers to develop effective policies. More information can be found at the Missouri Department of Labor.
The Landing, MO has seen a concerted effort from local and state governments to address its drug problem. The Warren County Health Department has initiated multiple outreach programs focusing on education and prevention. State-wide collaborations have also been established to streamline rehabilitation services and support.
Federal agencies like the Substance Abuse and Mental Health Services Administration (SAMHSA) also provide vital resources and funding aimed at reducing drug abuse in the area. These initiatives include funding local treatment centers and increasing access to mental health care.
Recent operations by local law enforcement in The Landing, MO, have been significant in tackling the drug trade. In a major bust in May 2023, police recovered sizable quantities of methamphetamine and fentanyl, leading to the arrest of a prominent drug trafficker.
The Landing hosts various community-driven events aimed at preventing drug abuse, such as annual awareness rallies and workshops organized by the Warren County Coalition for Prevention. These events are designed to educate the public on the dangers of drug use and promote healthier alternatives.
Accredited Drug Testing offers fast, reliable employment screening services in The Landing, MO. Trusted by employers nationwide for accurate results and exceptional service.
MO-HOPE Project
Comprehensive Mental Health Services, Inc.
Prevention Consultants of Missouri
NCADA
Reality House Programs, Inc.
Missouri Department of Mental Health
Compass Health Network
Alcoholics Anonymous Missouri
Missourinet
The Noon Project
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Time was running out before my Cdl got downgraded because of a violation I had on clearinghouse. I couldn't find an employer to send me for my return to duty test, but these guys had my test scheduled and done in the same day! They saved my cdl. Thank you again!
Michael Williams - 12/2/2024
I always have a good experience setting up company driver drug screens through ADT. I'm really happy I found them while searching online, they have made my job much easier.
Exodus Heath - 2/13/2025
I use their service for new hire and DOT employee's. Spoke with Taisha Walker this morning, and she was very helpful. She made the process smooth and seamless.
Christina Galdos - 3/9/2025