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Accredited Drug Testing provides a full range of drug and alcohol screening services at our 36 testing centers near Brielle, New Jersey. Our offerings include DOT and non-DOT urine drug tests, breathalyzer alcohol testing, EtG alcohol screening, and hair drug tests. We serve individuals, employers, and legal professionals with quick turnarounds and SAMSA-certified lab analysis, with same-day service options. Most of our Brielle testing sites are conveniently located a short distance from your residence or workplace. We also perform Occupational Health Tests, Clinical Evaluations, and Background Checks.
To arrange a test, call (800) 221-4291 or visit us online. Choose your desired test and select a convenient location. Testing services are accessible for personal use, employees, or others. Booking a test is simple and efficient; contact our scheduling team or set up your appointment online anytime. Our intuitive process allows seamless drug testing arrangements near Brielle.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Brielle drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Brielle, Monmouth County, 15% of high school students reported using prescription drugs non-medically in 2022.
Monmouth County saw a 7% increase in opioid overdose deaths from 2021 to 2022, impacting communities like Brielle.
The Brielle Police Department reported 50 drug-related arrests in the first half of 2023.
In 2022, Monmouth County had 510 Narcan deployments, with several incidents occurring in Brielle.
A 2021 report indicated that 20% of Brielle residents seeking addiction treatment were admitted for heroin abuse.
Brielle, part of Monmouth County, saw a 12% rise in rehab admissions for methamphetamine abuse in 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Brielle, NJ, adhere to strict drug testing policies to ensure workplace safety and productivity. Most organizations follow guidelines set by the Substance Abuse and Mental Health Services Administration (SAMHSA), conducting pre-employment and random drug screenings.
Policies often range from zero-tolerance to more supportive approaches, offering employees access to employee assistance programs for those seeking help. Businesses frequently collaborate with local rehab centers, such as New Hope Integrated Behavioral Health Care, to provide resources for their staff.
State laws also impact drug testing practices in Brielle. The New Jersey Department of Labor and Workforce Development provides guidelines for employers to implement fair and legal drug testing procedures while taking care to respect employee privacy rights.
The government has implemented several initiatives to combat drug abuse in Brielle, NJ. The New Jersey Office of the Attorney General collaborates with local law enforcement to increase patrols and establish drug-free school zones. The Monmouth County Officials are actively involved in community outreach programs, aiming to raise awareness about the dangers of drug abuse.
Local government efforts also include partnerships with the Jewish Family & Children's Service of Monmouth County, which provides counseling services for individuals and families affected by drug use. Additionally, Brielle benefits from state programs like the New Jersey Department of Health's Substance Use Disorder Treatment Program, which offers comprehensive treatment options.
Brielle, NJ, has witnessed several notable drug-related events that underscore the ongoing challenges of substance abuse in the area. Recent drug busts have focused on dismantling local distribution networks. For instance, a significant operation in 2023 led to the arrest of a ring dealing in opioids and methamphetamines.
Local law enforcement continues to remain vigilant, with initiatives such as the 'Operation Clean Sweep' aimed at reducing street-level drug sales in the community. This ongoing effort resulted in multiple arrests in 2022, curtailing the availability of narcotics within Brielle.
Community events like the 'Brielle Drug Awareness Fair' help educate residents about substance abuse risks and resources. This event is held annually to promote anti-drug campaigns and provide information on rehabilitation services available locally.
Accredited Drug Testing offers fast, reliable employment screening services in Brielle, NJ. Trusted by employers nationwide for accurate results and exceptional service.
New Jersey DOT/Non DOT Physicals
SAMHSA
NJ Dept of Health: Substance Use Disorder Treatment
NJ Office of the Attorney General
NCADD-New Jersey
Jewish Family & Children's Service of Monmouth County
New Hope IBHC
Monmouth County Library System
Ocean Mental Health Services
NJ Department of Labor
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024