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Offering a wide array of drug and alcohol testing solutions, Accredited Drug Testing operates 37 centers in the Matawan, NJ vicinity. Our services encompass both DOT and non-DOT urine analyses, breath and EtG alcohol assessments, as well as hair follicle drug examinations tailored for personal, corporate, and legal purposes. In Matawan, NJ, we guarantee fast result turnaround with options for same-day service and adhere to SAMSA certifications. Our centers, conveniently located, are typically just a short drive from your residence or workplace. We also provide Occupational Health, Clinical Testing, and conduct Background Checks.
Reach out at (800) 221-4291 or simply register on our platform. Choose your preferred test type and pick a local center—whether testing for yourself, staff, or others. The process is swift and straightforward; contact our scheduling team or set up your test online any time of day. Thanks to our efficient, user-focused approach, arranging a drug test in Matawan is hassle-free.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Matawan drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2022, Matawan, NJ, located in Monmouth County, reported a 15% rise in opioid-related deaths.
Monmouth County hospitals recorded over 600 drug overdose cases in 2022, with a significant number coming from Matawan.
Matawan, NJ's treatment centers saw a 20% increase in admissions for drug abuse in the last year.
Matawan law enforcement seized over 500 grams of heroin in 2022.
In 2023, more than 50% of Matawan's drug-related arrests involved individuals aged 18-25.
Monmouth County, including Matawan, launched 10 new drug prevention programs in 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Matawan, NJ, are increasingly incorporating drug testing policies to ensure workplace safety. Many companies are adopting pre-employment and random drug testing practices to deter substance abuse. Such measures are guided by both state and federal guidelines, including those by the Substance Abuse and Mental Health Services Administration (SAMHSA).
These policies are designed not only for safety but to boost overall productivity. By ensuring a drug-free workplace, employers aim to reduce accidents and healthcare costs related to substance abuse, benefiting both employees and the organization.
The government's response to drug issues in Matawan, NJ, includes enhanced funding for local treatment centers and prevention programs. Collaboration with New Jersey Department of Health plays a crucial role in providing resources and support.
Local authorities have been keen on partnerships with federal bodies such as the DEA to curb drug trafficking. This collaboration has led to multiple successful operations and a decline in availability of illicit substances within Matawan.
In Matawan, NJ, local law enforcement agencies have been actively involved in combating drug-related activities. Recent operations have focused on dismantling small-scale drug distribution networks operating within the community. The police have intensively collaborated with neighboring jurisdictions to address cross-regional drug trafficking issues.
Authorities have reported several instances where community tip-offs led to the successful arrest of drug dealers. These initiatives underscore the importance of vigilance and community cooperation in tackling drug-related crimes. The police are committed to raising awareness through neighborhood programs to ensure the safety and wellbeing of residents.
Another significant drug bust in Matawan involved a coordinated effort resulting in the seizure of substantial quantities of illegal substances. This operation disrupted a major supply chain, adversely affecting the local market for illicit drugs. Officials continue to investigate to uncover the larger networks behind these operations, emphasizing the ongoing challenge these threats pose to the community.
Accredited Drug Testing offers fast, reliable employment screening services in Matawan, NJ. Trusted by employers nationwide for accurate results and exceptional service.
New Jersey DOT/Non DOT Physicals
New Jersey Department of Human Services
NJ CARE Plus
Monmouth County Health Department
Bridgeway Behavioral Health Services
Princeton House Behavioral Health
Ocean Mental Health Services
PerformCare NJ
Health Solutions NJ
New Jersey Office of the Attorney General
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024