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Comprehensive drug and alcohol screening is conveniently accessible at our 30 Middlesex locations in New Jersey through Accredited Drug Testing. With offerings including DOT and non-DOT urine tests, breathalyzers, EtG evaluations, and hair testing, we cater to personal, employment, and legal requirements. Rapid results are available for Middlesex area residents, featuring SAMSA certified lab testing and same-day service. Most centers are strategically located near your residence or workplace. Our suite of services further extends to Occupational Health Testing, Clinical Testing, and Background Check analysis.
Dial (800) 221-4291 or register on our site. Select your desired test and location, whether for personal, employee, or third-party testing. Our scheduling system is designed for speed and simplicity, offering 24/7 online booking or direct contact with our scheduling team. Organizing drug testing in Middlesex is a breeze with our seamless, user-focused procedure.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Middlesex drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Middlesex County, NJ saw a 15% increase in opioid-related deaths in 2022.
In 2022, Middlesex County reported over 400 opioid overdoses.
Middlesex, NJ had a 30% rise in drug-related emergency room visits last year.
Approximately 2,500 residents in Middlesex County sought treatment for substance abuse in 2021.
The city of Middlesex, in Middlesex County, recorded 60 heroin possession arrests in 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
In Middlesex, NJ, many employers enforce rigorous drug testing policies to maintain a safe work environment. Random drug testing and pre-employment screenings are standard across various sectors. Employers must comply with state regulations provided by the New Jersey Department of Labor.
Larger firms in Middlesex also offer employee assistance programs (EAPs) that include counseling and support for substance abuse issues. These programs aim to help employees overcome addiction while maintaining job security.
Small businesses often partner with local healthcare providers to offer workshops on substance abuse awareness. This proactive approach not only helps in early detection but fosters a supportive workplace culture.
The government of Middlesex County, NJ has implemented several initiatives to combat drug abuse. These include expanded funding for local rehabilitation centers and education programs in schools to prevent drug use. Middlesex County Prosecutor's Office oversees these efforts.
Statewide, the New Jersey Department of Health provides grants to community organizations focused on drug abuse prevention and recovery services. The county collaborates with these entities to enhance access to care and support.
The Middlesex County Prosecutor's Office announced the successful dismantling of a major drug trafficking ring operating in the region. This operation, carried out by local law enforcement agencies, led to multiple arrests and the seizure of substantial quantities of illicit substances, including heroin and methamphetamine, highlighting the ongoing efforts to curb drug distribution in Middlesex, NJ.
In a collaborative effort, Middlesex police, along with state and federal agencies, executed a series of coordinated raids targeting known narcotic hotspots. These actions stemmed from months of investigation and surveillance, underscoring the commitment to tackling drug-related crime, and resulted in the confiscation of several firearms and large sums of cash linked to drug sales.
A public awareness campaign has been launched in Middlesex, NJ, aiming to educate residents about the dangers of opioid addiction and the resources available for those affected. This initiative includes community forums and educational workshops designed to empower individuals with the knowledge needed to combat substance abuse effectively and safely within the community.
Accredited Drug Testing offers fast, reliable employment screening services in Middlesex, NJ. Trusted by employers nationwide for accurate results and exceptional service.
New Jersey DOT/Non DOT Physicals
New Jersey Division of Mental Health and Addiction Services
Middlesex County Drug and Alcohol Information
Horizon NJ Health Drug Abuse Treatment
New Jersey Cornerstone Addiction Treatment
RWJBarnabas Health Addiction Treatment
Police Assisted Addiction and Recovery Initiative
Carnegie Center for Addiction Treatment
Behavioral Health Resources and Services
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024