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Accredited Drug Testing provides a variety of drug and alcohol examination services through our 31 locations in North Middletown, New Jersey. We conduct DOT and non-DOT urine analyses, breathalyzer evaluations, EtG alcohol checks, and hair follicle screenings for personal, employer, and legal purposes. Across North Middletown, NJ, we offer rapid testing outcomes and SAMSA-endorsed lab evaluations with the convenience of same-day appointments. Our drug testing facilities are typically just a short distance from your workplace or residence. We also specialize in Occupational Health Testing, Clinical Analysis, and Background Screening.
To get started, dial (800) 221-4291 or complete your registration online. Pick your preferred test and find the nearest test center—services are offered for personal, employee, or third-party testing. Setting an appointment is simple and quick, either by contacting our scheduling team or booking through our online service available any time. The process is straightforward, ensuring that arranging drug testing near North Middletown is hassle-free.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our North Middletown drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2023, Monmouth County reported over 500 opioid-related hospital visits, illustrating the drug crisis in North Middletown, NJ.
North Middletown, NJ, saw a 15% increase in drug arrests over a two-year period ending in 2023.
Monmouth County registered 250 drug overdose deaths in 2022, many occurring in areas such as North Middletown, NJ.
Approximately 20% of the youth in Monmouth County, where North Middletown, NJ is located, reported attempting drugs at least once by 2022.
In 2023, surveys indicated that 30% of North Middletown, NJ residents consider drug abuse a major community issue.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in North Middletown, NJ, have implemented stringent drug testing policies to maintain a safe and productive workplace. Many follow guidelines established by the U.S. Department of Labor to ensure compliance and fairness.
Local businesses often conduct pre-employment, random, and post-accident drug testing. This approach, while ensuring workplace safety, also reflects broader societal efforts to minimize drug use and its impact on employment.
In addition, job training programs, in collaboration with entities like the New Jersey Department of Labor, sometimes incorporate education on substance abuse, aiming to prepare job seekers for a drug-free career path.
The government has been aggressively tackling drug issues in North Middletown, NJ, particularly through initiatives led by the Monmouth County Health Department. Grants from state and federal sources, such as those awarded by the Substance Abuse and Mental Health Services Administration, have played a vital role in expanding prevention programs and treatment facilities.
Collaborative efforts with the New Jersey Office of the Attorney General have also enhanced law enforcement strategies, aiming to reduce drug-related crimes and promote community safety. Continuous community outreach programs seek to educate the public and foster a supportive environment for recovery.
Recent local drug busts in North Middletown, NJ, underscore the ongoing battle against drug trafficking in Monmouth County. In early 2023, a large operation led to numerous arrests, disrupting a significant supply chain distributing opioids in the area.
Community events, such as drug take-back days organized by local law enforcement, continue to encourage residents to dispose of unused medications safely, thereby reducing potential abuse.
Educational seminars on drug prevention and awareness are regularly held at community centers, often in partnership with the Monmouth County Sheriff's Office, highlighting the community's proactive stance on addressing drug abuse.
Accredited Drug Testing offers fast, reliable employment screening services in North Middletown, NJ. Trusted by employers nationwide for accurate results and exceptional service.
New Jersey DOT/Non DOT Physicals
Partnership for a Drug-Free New Jersey
NJ 211 Substance Abuse Resources
Drug Abuse in New Jersey
Monmouth ResourceNet
Ocean ResourceNet
NJ Medication Assisted Treatment
National Council on Alcoholism and Drug Dependence - NJ
Monmouth County Health Department
Nar-Anon New Jersey
Prevention First NJ
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024