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At our 38 Saddle River, NJ area sites, Accredited Drug Testing delivers extensive drug and alcohol assessment services. We conduct both DOT and non-DOT urine drug testing, breath alcohol exams, EtG alcohol assessments, and hair follicle drug screenings catering to personal, corporate, and legal audiences. Rapid result options and SAMSA-certified lab analyses are offered, with same-day service usually available. Most testing centers are conveniently located near your residence or workplace in Saddle River. We also provide Occupational Health Tests, Clinical Tests, and Background Verification services.
To schedule a test, dial (800) 221-4291 or register through our website. Just pick your preferred test and a convenient location—services are open for your own use, or for employers and third parties. Organizing a test is Fast and Effortless; contact our scheduling team by phone or book online anytime. Our efficient and intuitive procedure ensures easy scheduling of drug assessments near Saddle River.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Saddle River drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Saddle River, Bergen County, sees 15% of opioid overdoses in young adults aged 18-25.
Bergen County, including Saddle River, reports a 20% increase in drug-related arrests in 2022.
Naloxone administration rose by 25% in Saddle River, Bergen County in 2021.
Saddle River, Bergen County, noted a 12% rise in rehab admissions in 2022.
High school drug use in Saddle River, Bergen County is at 18%, slightly above the state average.
Prescription drug misuse in Saddle River, Bergen County accounts for 30% of all drug abuse cases.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Saddle River, NJ, are increasingly implementing strict drug testing policies to ensure a safe and productive workplace. These policies often involve pre-employment screenings and random drug tests to deter substance abuse among employees. Companies partner with local testing agencies for efficient and reliable testing procedures.
Adhering to both state and federal guidelines, many employers include drug education programs as part of their employee wellness initiatives. This proactive approach aims to support employees who may struggle with substance abuse and offers resources for rehabilitation and counseling. More information on state guidelines can be found at the New Jersey Department of Labor and Workforce Development's website New Jersey Department of Labor and Workforce Development.
The government of Saddle River, NJ, in the heart of Bergen County, is actively working to combat drug abuse. Initiatives include increased funding for local drug prevention programs and enhanced collaboration with healthcare providers. The Bergen County Division of Mental Health and Addiction Services Bergen County Division of Mental Health and Addiction Services supports various community-based efforts.
Additionally, law enforcement agencies in Saddle River collaborate with the state's Governor's Council on Alcoholism and Drug Abuse Governor's Council on Alcoholism and Drug Abuse to implement evidence-based interventions. These efforts are designed to reduce drug availability and increase public awareness about the dangers of drug misuse.
Saddle River has seen several notable drug-related events over recent years. One high-profile case involved the dismantling of a local drug ring in Bergen County, leading to multiple arrests and confiscation of significant quantities of illegal substances. This operation was part of a larger statewide crackdown coordinated by the New Jersey State Police New Jersey State Police.
Community awareness events, like 'Drug Take-Back Day,' are regularly held in Saddle River to encourage residents to dispose of unused medications safely. These events not only reduce the risk of drug misuse but also foster community involvement in tackling the complex issue of drug abuse.
Accredited Drug Testing offers fast, reliable employment screening services in Saddle River, NJ. Trusted by employers nationwide for accurate results and exceptional service.
New Jersey DOT/Non DOT Physicals
Partnership for a Drug-Free New Jersey
Bergen County Division of Mental Health and Addiction Services
National Council on Alcoholism and Drug Dependence - New Jersey
Governor's Council on Alcoholism and Drug Abuse
New Jersey Division of Mental Health and Addiction Services
ReachNJ
SAMHSA National Helpline
Treatment Services in New Jersey
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024