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At our 37 testing centers in the Carle Place, NY region, Accredited Drug Testing delivers extensive drug and alcohol screening services. We administer DOT-regulated and non-regulated urine drug tests, breathalyzer alcohol evaluations, EtG alcohol analysis, and drug analysis using hair samples, catering to individual needs, company requirements, and legal purposes. With quick testing results offered in Carle Place, NY along with SAMSA authorized lab examinations, same-day appointments can be arranged. Most testing sites in Carle Place are conveniently located within a short distance from your home or workplace, and we also conduct Occupational Health Testing, Clinical Testing, and Background Verifications.
To book a test, dial (800) 221-4291 or proceed with online registration. Select your required test and find a conveniently located center—available for personal, employee, or third-party testing. The process of arranging a test is swift and straightforward; reach out to our scheduling team or confirm your booking online at any hour. Our seamless system makes it easy to organize drug screenings near Carle Place efficiently.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Carle Place drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2019, Nassau County reported a 12% increase in drug overdose deaths, impacting Carle Place.
Carle Place, located in Nassau County, had a 25% rise in treatment admissions for opioid use in 2020.
In 2021, Nassau County's opioid overdose rate was 14.9 per 100,000 people, affecting communities like Carle Place.
In 2018, 30% of Nassau County's drug-related arrests occurred within a 10-mile radius of Carle Place.
Carle Place observed a 15% increase in naloxone administration by first responders in 2020, according to Nassau County data.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Carle Place, NY, adhere to drug testing policies to maintain a safe and productive work environment. Many businesses follow guidelines set by the Drug-Free Workplace Act, which encourages employers to establish drug-free policies and conduct drug testing.
Local businesses often consult with the New York State Department of Labor for advice on implementing compliant drug testing procedures. These policies aim to reduce the impact of substance abuse on the workforce and ensure a safer community for all residents of Carle Place.
The government has implemented several measures to combat drug problems in Carle Place, NY. Through initiatives funded by the Nassau County Department of Human Services, efforts focus on prevention, treatment, and recovery support. Collaboration with the New York State Office of Addiction Services and Supports (OASAS) enhances local strategies to curb drug abuse.
The New York State Department of Health also plays a role in addressing substance abuse through policy-making and funding programs. State and federal grants assist local agencies in Carle Place to implement community-based solutions and raise awareness about the dangers of drug abuse.
Carle Place, NY, has seen several drug-related events, drawing attention to the ongoing challenges of substance abuse. In 2022, a significant drug bust led by the Nassau County Police Department resulted in the seizure of multiple narcotics and the arrest of several suspects, highlighting the community's commitment to fighting drug crime.
The Nassau County District Attorney's Office plays a crucial role in prosecuting drug offenses, working closely with local law enforcement to prevent drug distribution and usage within Carle Place. Public forums and community events are organized regularly to educate residents about the risks of drug abuse and encourage preventive measures.
Accredited Drug Testing offers fast, reliable employment screening services in Carle Place, NY. Trusted by employers nationwide for accurate results and exceptional service.
Council on Addiction, Nassau County
Long Island Council on Alcoholism and Drug Dependence (LICADD)
Phoenix House New York
New York State Office of Addiction Services and Supports (OASAS)
Alcoholics Anonymous
Narcotics Anonymous
SAMHSA National Helpline
Facing Addiction with NCADD
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024