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Accredited Drug Testing provides a wide range of drug and alcohol screening services across 30 centers in the Lincolndale, NY area. Our services include DOT and non-DOT urine drug testing, breath and EtG alcohol tests, and hair drug screening for individual, professional, and legal purposes. We offer expedited testing and SAMSA certified lab analysis in Lincolndale, NY with the convenience of same-day service. Most locations are accessible within minutes from your home or workplace, with additional offerings such as Occupational Health Testing, Clinical Testing, and Background Checks.
Reach us at (800) 221-4291 or register through our website. Choose your test type and select a convenient center nearby—testing services are offered for yourself, your employees, or another individual. Scheduling is quick and hassle-free, either call our scheduling team or book online anytime. Our efficient process makes arranging drug testing near Lincolndale simple and seamless.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Lincolndale drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Lincolndale, located in Westchester County, has seen a 20% increase in opioid overdoses over the past five years.
Westchester County reports that approximately 15% of Lincolndale teens have tried marijuana by age 16.
In Lincolndale, Westchester County, prescription drug abuse rates have risen by 10% since 2020.
A 2021 survey showed that 5% of Lincolndale residents in Westchester County struggle with substance abuse disorders.
Lincolndale's drug-related hospitalizations account for 8% of Westchester County's total numbers, according to a 2022 report.
The overdose mortality rate in Lincolndale, Westchester County, has remained relatively stable at 2 fatalities per 10,000 people.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Lincolndale, NY, are taking significant measures to ensure a drug-free workplace. Many companies follow strict drug-testing policies as part of their hiring process in accordance with guidelines from the U.S. Department of Labor. These tests aim to deter drug use and maintain productivity and safety in the workplace.
Beyond pre-employment screening, several organizations in Lincolndale implement random drug testing, especially within industries such as transportation, healthcare, and education. This approach is designed to uphold safety standards and comply with state regulations. Employees who test positive or refuse testing are often referred to employee assistance programs to help with recovery.
The town of Lincolndale, NY, in Westchester County, is working closely with local and state initiatives to combat drug abuse. Programs such as New York State Office of Addiction Services and Supports provide crucial resources and funding for prevention and recovery efforts in the area. These efforts are designed to reduce the availability and appeal of drugs among the youth and general population.
Moreover, partnerships with community stakeholders and health services are established to increase awareness and education about the risks of drug abuse. Initiatives include workshops and community events funded by Westchester County's health department. For more detailed information, visit the Westchester County Department of Health website.
Recently, Lincolndale witnessed a significant drug bust involving local law enforcement and the county's crime task force. These operations have resulted in the arrest of several individuals who were part of a broader drug trafficking network. Authorities confiscated considerable quantities of illegal substances, thereby disrupting supply chains that extended within and beyond Lincolndale.
Such operations are part of a larger strategy led by the Westchester County District Attorney's office, focusing on curbing drug trade activities. Community support has been pivotal to these efforts, exemplified by neighborhood watch initiatives and tips from residents leading to successful interventions. For more details, the county's strategic operations can be found on the Westchester County District Attorney's website.
Accredited Drug Testing offers fast, reliable employment screening services in Lincolndale, NY. Trusted by employers nationwide for accurate results and exceptional service.
New York State Office of Addiction Services and Supports
Westchester County Department of Health
Substance Abuse and Mental Health Services Administration
Community Action for Drug Prevention
NYU Langone Health
City of Yonkers Health & Human Services
New York Cares
Mount Sinai Health System
New York Connects
Hudson Valley Community Services
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024