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Accredited Drug Testing delivers extensive drug and alcohol testing services at 32 Glen Alpine, North Carolina locations. We handle both DOT and non-DOT urine screenings, breath alcohol tests, EtG alcohol assessments, and hair drug tests, catering to individuals, businesses, and legal requirements. In Glen Alpine, NC, we provide quick-result testing alongside SAMSA certified lab analyses. Same-day options are often available, with most Glen Alpine facilities conveniently located near you. Additional offerings include Occupational Health Testing, Clinical Testing, and Background Checks.
Dial (800) 221-4291 or register online. Choose your required test and a nearby center—available for individual, employee, or third-party testing. Setting up a test is Quick and Simple, through our scheduling team or via our 24/7 online system. Our efficient and straightforward service makes organizing nearby drug assessments in Glen Alpine easy and hassle-free.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Glen Alpine drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2022, Burke County, where Glen Alpine is located, reported a 15% increase in opioid-related deaths.
A 2021 survey indicated 25% of high school students in Glen Alpine had used marijuana at least once in the past year.
The percentage of Glen Alpine residents seeking drug treatment rose by 10% in 2023 compared to previous years.
Burke County's narcotics officers reported seizing over 50 pounds of methamphetamine in 2021.
20% of arrests in Glen Alpine in 2022 were related to drug offenses.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Glen Alpine, NC, place a significant emphasis on maintaining drug-free work environments. Many local businesses implement regular drug testing policies as part of their hiring and ongoing employment practices. These policies help ensure workplace safety and boost morale among employees.
Local employers may also collaborate with organizations such as the U.S. Department of Labor to stay informed about legal requirements and best practices related to drug testing. Testing methods typically include urine, saliva, or hair follicle tests, conducted under strict privacy and confidentiality protocols.
Through maintaining stringent drug policies, businesses in Glen Alpine strive to reduce the risks associated with substance abuse, while promoting productivity and well-being among their workforce. These measures are part of a broader effort to address drug-related issues in the community at large.
The government of Glen Alpine, NC, is actively working to combat drug problems through various initiatives. Programs focus on prevention, education, and rehabilitation services, collaborating with organizations like North Carolina Department of Health and Human Services. Partnerships aim to reduce drug availability and offer community support. Efforts also include expanding local law enforcement resources and improving response capabilities for drug-related incidents.
State-level strategies include the implementation of the North Carolina Opioid Action Plan, which targets decreasing opioid misuse and overdoses. The North Carolina Opioid Prevention initiative hosts training sessions, supports prescription drug take-back events, and enhances the availability of treatment and recovery options for affected individuals. These collaborative efforts aim to create a healthier community in Glen Alpine.
Glen Alpine, NC, has been the scene of several notable drug busts in recent years, showcasing both the prevalence of drug activity and the vigilance of local law enforcement. A significant operation in 2022 led to the confiscation of substantial quantities of methamphetamine, resulting in multiple arrests.
These incidents underline law enforcement's commitment to tackling drug crime in the area. With the assistance of regional and state agencies, officers in Glen Alpine work tirelessly to dismantle drug networks and prevent future trafficking.
Community events often focus on awareness, education, and cooperation between residents and police. These collaborative efforts help ensure that Glen Alpine remains a safe and welcoming place for families and businesses.
Accredited Drug Testing offers fast, reliable employment screening services in Glen Alpine, NC. Trusted by employers nationwide for accurate results and exceptional service.
North Carolina DOT/Non DOT Physicals
NC DHHS: Mental Health & Substance Abuse
NC o-drug Epidemic Response
Justice Center: Problem of Substance Use Disorders
Burke County Substance Abuse Resources
Project Lazarus
NC Prevention Partners
Phoenix House North Carolina
Carolina Center for Recovery
USA Recovery Network
Caron Treatment Centers - NC
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024