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Accredited Drug Testing offers a wide range of drug and alcohol testing services at our 30 locations around Granite Falls, NC. Our services include both DOT and non-DOT urine tests, breathalyzer tests, EtG alcohol checks, and hair drug tests suitable for personal, corporate, or legal purposes. For rapid results, Granite Falls residents can rely on our testing facilities, which provide quick, SAMSA-certified lab analyses with same-day service options. Many of our clinics are conveniently situated close to you. Our service repertoire also features Occupational Health Testing, Clinical Assessments, and Background Verification.
Dial (800) 221-4291 or sign up on our website. Just pick your required test and pinpoint a nearby facility—testing options exist for personal use, staff, or others. Our scheduling process is swift and straightforward, allowing you to reserve tests via phone or online at any time, 24/7. With our efficient and easy-to-use system, arranging drug testing near Granite Falls becomes a hassle-free task.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Granite Falls drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2021, Granite Falls, located in Caldwell County, NC, reported a significant rise in opioid-related overdoses by 15%.
Caldwell County, encompassing Granite Falls, saw a 10% increase in drug-related hospital admissions in 2022.
In a 2021 survey in Caldwell County, 25% of high school students in Granite Falls admitted to trying marijuana.
Granite Falls Police Department recorded a 20% rise in drug-related arrests in 2022 within Caldwell County.
In 2022, 30% of reported domestic violence cases in Caldwell County involved substance abuse in Granite Falls.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Granite Falls, NC, adopt stringent drug testing policies to ensure workplace safety. Many companies follow guidelines from the U.S. Department of Labor, conducting pre-employment, random, and post-incident tests.
These policies reflect a commitment to reducing the impact of substance abuse on productivity and safety, with staff receiving regular training on drug use prevention and identifying signs of substance abuse among colleagues.
The government of Granite Falls and Caldwell County have intensified efforts to combat drug issues through various programs. Enhanced funding has been allocated to state addiction services and local rehabilitation facilities, ensuring those affected receive adequate help.
Caldwell County has increased collaboration with the CDC and local health departments to implement better prevention programs in Granite Falls, focusing on education and community support.
Recent law enforcement activities in Granite Falls, NC, have led to significant drug busts. In 2023, a joint operation between local police and county sheriffs resulted in the seizure of large quantities of methamphetamine.
Public awareness campaigns and police reports in Granite Falls highlight these events to inform and engage the community, reinforcing the importance of vigilance and cooperation in tackling this ongoing issue.
Accredited Drug Testing offers fast, reliable employment screening services in Granite Falls, NC. Trusted by employers nationwide for accurate results and exceptional service.
North Carolina DOT/Non DOT Physicals
North Carolina Department of Health and Human Services
Mountain Area Health Education Center
Jaycee Homes
National Council on Alcoholism and Drug Dependence
Drug Rehab
Insight on Recovery
The Counseling Group
WNCCHS Substance Use Services
Quickly find trusted local drug testing centers in Granite Falls, NC — fast, convenient, and reliable every time!
Quickly find a local DOT drug testing center in Granite Falls, NC — fast, reliable, convenient nationwide service!
DNA testing for legal and non-legal purposes including child support, and child custody around Granite Falls, NC.
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Get fast, accurate hair drug testing at our convenient Granite Falls, NC locations—results you can trust, every time!
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Reliable nationwide drug testing services ensuring accuracy, compliance, and quick results for businesses and individuals in Granite Falls, NC.
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Certified DOT physicals with quick, reliable exams to keep Granite Falls, NC drivers compliant and on the road with confidence.
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024