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Accredited Drug Testing delivers a wide array of drug and alcohol testing solutions across 35 testing facilities in Lattimore, North Carolina. Catering to both DOT and non-DOT requirements, we conduct urine drug tests, breathalyzer alcohol exams, EtG testing, and hair analysis for personal, business, and legal purposes. Experience swift results and SAMSA-certified lab evaluations, with the convenience of same-day services. Our Lattimore, NC sites are located just minutes from most homes or offices. We further provide Occupational Health Testing, Clinical Testing, and Background Checks.
To arrange your test, dial (800) 221-4291 or register online. Choose your specific test type and find a location close to you—ideal for self-testing, employee screening, or third-party testing. The process is quick and straightforward; contact our scheduling team or book online anytime, day or night. Our efficient system makes organizing drug testing near Lattimore simple and hassle-free.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Lattimore drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2022, Cleveland County reported a 15% increase in opioid-related overdoses, including cases from Lattimore, NC.
Lattimore, in Cleveland County, saw a 7% rise in methamphetamine seizures during 2021.
In Cleveland County, where Lattimore is located, 30% of drug-related crimes in 2021 involved prescription drugs.
Lattimore's Cleveland County experienced a 12% decrease in heroin-related arrests in 2022.
Cleveland County reported that Lattimore contributes to 5% of its total drug seizure cases.
In 2023, Cleveland County ranked among the top 10 in North Carolina for opioid prescriptions per capita, affecting towns like Lattimore.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Lattimore, NC, are increasingly implementing strict drug testing policies to ensure a safe and productive work environment. These policies often include pre-employment screening and random testing for employees. According to the U.S. Department of Labor, maintaining a drug-free workplace is a priority for many businesses.
Local businesses align with the North Carolina Department of Labor's recommendations in adopting comprehensive drug-testing policies. This approach not only helps decrease substance abuse among employees but also reduces legal liabilities for the companies. Employers are encouraged to educate their workforce about the dangers of drug misuse.
The government has launched initiatives to combat drug abuse in Lattimore, NC, within Cleveland County. Key efforts include partnerships with local law enforcement and health agencies to increase awareness and education on drug dangers. Visit the Cleveland County Health Department for more information on local programs.
State efforts are also in place, with North Carolina's collaboration with federal agencies like the Substance Abuse and Mental Health Services Administration (SAMHSA) to provide resources for addiction treatment and prevention. These efforts are part of a broader strategy to minimize the impact of drug abuse in communities, including Lattimore.
In recent years, Lattimore, NC, has witnessed several significant drug busts as part of Cleveland County's ongoing battle against drug abuse. In 2022, a large-scale operation led to the arrest of multiple individuals involved in meth distribution across the area. These activities have brought attention to the local efforts in eradicating illegal substances.
Additionally, Cleveland County law enforcement conducted a series of raids targeting opioid distributors in 2023, successfully seizing a substantial quantity of illicit drugs. These efforts highlight the dedication of the community and law enforcement in Lattimore to combat drug-related crimes actively.
Accredited Drug Testing offers fast, reliable employment screening services in Lattimore, NC. Trusted by employers nationwide for accurate results and exceptional service.
North Carolina DOT/Non DOT Physicals
National Council on Alcoholism and Drug Dependence (NCADD)
Cleveland County Health Department
Substance Abuse and Mental Health Services Administration (SAMHSA)
North Carolina Department of Health and Human Services
Partnership for Drug-Free Kids in North Carolina
State of North Carolina Government
Drug Rehab Centers in North Carolina
U.S. Department of Labor Drug-Free Workplace
North Carolina Health News
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024