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Accredited Drug Testing delivers extensive drug and alcohol testing services across 38 testing sites within the East Pittsburgh region of Pennsylvania. Our offerings cater to both DOT and non-DOT requirements, including urine drug testing, breath alcohol screening, EtG alcohol analysis, and hair drug assessments, suitable for individuals, employers, or legal purposes. In East Pittsburgh, PA, we ensure quick result testing and laboratory analysis accredited by SAMSA, with same-day service options. The majority of our testing facilities are conveniently located near your residence or office. We also provide Occupational Health Services, clinical assessments, and background verification.
To get started, dial (800) 221-4291 or proceed with online registration. After selecting your desired test, pick a location nearby—services are available for personal, employee, or third-party testing. Booking your test is quick and straightforward: reach out to our scheduling team or manage your appointment online anytime. Our hassle-free process makes arranging a drug test near East Pittsburgh simple and efficient.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our East Pittsburgh drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In East Pittsburgh, Allegheny County, opioid-related overdoses accounted for 61% of all substance abuse fatalities in 2022.
East Pittsburgh, Allegheny County saw a 15% increase in synthetic drug-related incidents between 2021 and 2022.
In 2022, East Pittsburgh recorded 320 cases of drug possession, according to Allegheny County Police.
Alcohol-induced disorders in East Pittsburgh, Allegheny County were reported at a rate of 34 per 10,000 residents in 2022.
In 2022, East Pittsburgh had 125 arrests linked to methamphetamine distribution, as stated by Allegheny County Department of Corrections.
According to the Allegheny County Department of Health, East Pittsburgh had a 9% increase in cannabis-related hospital visits in 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
In response to the widespread drug issues, employers in East Pittsburgh, PA, have increasingly implemented drug testing policies to maintain a safe and productive work environment. These policies align with state guidelines provided by the PA Department of Labor & Industry, ensuring compliance and fairness. Employers conduct pre-employment screenings and random checks, focusing on safety-sensitive positions.
Many businesses in East Pittsburgh collaborate with local healthcare providers to offer employee assistance programs. These programs encourage employees struggling with substance issues to seek help anonymously, reducing stigma and promoting rehabilitation. With the backing of organizations like the Substance Abuse and Mental Health Services Administration (SAMHSA), these initiatives aim to foster supportive work environments while upholding safety standards.
East Pittsburgh, located in Allegheny County, has been actively involved in efforts to curb drug abuse through several government initiatives. The Allegheny County Health Department regularly collaborates with local law enforcement to enhance community outreach programs aimed at prevention and education. These efforts are supported by state-level initiatives, which can be found on the PA.gov Opioid Epidemic Guide. East Pittsburgh is also a beneficiary of federal grants targeted at expanding local treatment facilities, which have shown promise in reducing drug-related issues.
In an effort to enhance community resilience, the local government in East Pittsburgh has partnered with organizations such as the Allegheny County Overdose Prevention initiative. Programs like these offer training sessions for overdose reversal and support services for affected individuals and families. The combination of local, state, and federal resources aims to create a comprehensive strategy to tackle drug problems in the area effectively.
East Pittsburgh, Allegheny County, recently witnessed a major drug bust when local authorities dismantled a large-scale methamphetamine ring. This operation, conducted in collaboration with the federal Drug Enforcement Administration (DEA), led to several arrests and the seizure of significant quantities of illegal substances, marking a significant win in the fight against drug trafficking.
Local community groups have held events aimed at raising awareness and educating residents about the dangers of drug abuse. The East Pittsburgh Community Center hosted a 'Say No to Drugs Fair', which featured guest speakers, informational booths, and interactive activities designed to engage both young people and adults in drug prevention efforts. Such events have become integral in fostering a community united against drug abuse.
Accredited Drug Testing offers fast, reliable employment screening services in East Pittsburgh, PA. Trusted by employers nationwide for accurate results and exceptional service.
Pennsylvania DOT/Non DOT Physicals
PA o-drug Epidemic Guide
Allegheny County Health Department
PA Department of Drug and Alcohol Programs
SAMHSA
ACR Health
Narcotics Anonymous
Allegheny County Adult Probation
Healthcare and Rehabilitation Services
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024