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Accredited Drug Testing delivers a broad array of drug and alcohol screening services at 30 different testing locations around South Bethlehem, Pennsylvania. We accommodate both DOT and non-DOT urine analyses, breath alcohol screenings, EtG alcohol evaluations, and hair drug testing fit for individuals, employers, and legal purposes. In South Bethlehem, PA, expect speedy service with rapid testing results and SAMSA certified lab analyses. Most testing sites are conveniently located near your home or office, and same-day services are offered. Our other services include Occupational Health Testing, Clinical Testing, and Background Checks.
Dial (800) 221-4291 or go online to register. Easily specify your preferred test and select a location near you—ideal for personal testing, employee assessments, or tests for another person. Arranging a test is quick and straightforward; our scheduling team is ready by phone, or you can easily book online 24/7. Our seamless, user-friendly system makes scheduling drug testing anywhere around South Bethlehem hassle-free.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our South Bethlehem drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In South Bethlehem, Northampton County, opioid-related overdose deaths increased by 15% from 2020 to 2021.
The city of South Bethlehem, Northampton County, reported over 300 drug-related arrests in 2021.
Approximately 8% of high school students in South Bethlehem, Northampton County, reported using illicit drugs in the past year.
Emergency room visits for drug overdoses in South Bethlehem, Northampton County, rose by 20% in 2022.
In 2022, South Bethlehem, Northampton County, participated in the National Prescription Drug Take Back Day, collecting over 500 pounds of unused medications.
South Bethlehem, Northampton County, saw a 10% increase in methamphetamine-related incidents in 2022.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in South Bethlehem, Northampton County, have adopted stringent measures to address drug use in the workplace. Many organizations implement mandatory drug testing policies in compliance with state regulations outlined by the Pennsylvania Government.
These policies are designed not only for safety but also to promote a healthy work environment. Employers work in tandem with local health departments to provide support and resources for employees struggling with substance abuse.
Businesses also offer educational sessions and access to counseling services, ensuring employees are aware of the resources available to them, thus maintaining a productive and drug-free workplace.
The government of South Bethlehem, Northampton County, has been proactive in addressing the drug problem through various initiatives. The city collaborates with the Drug Enforcement Administration to conduct regular drug-awareness campaigns and community workshops.
At the state level, Pennsylvania's Department of Drug and Alcohol Programs provides support for rehabilitation and prevention programs in South Bethlehem. The city also receives funds from federal grants to improve local drug treatment facilities.
In recent years, South Bethlehem, Northampton County, has seen several major drug busts that have disrupted illegal narcotic distribution networks. In 2022, local law enforcement conducted a series of successful raids, seizing large amounts of heroin and fentanyl destined for the area.
The city hosts annual events like the 'Night of Hope,' aimed at raising awareness about the impact of drug abuse and promoting community-based solutions to combat the issue. These events bring together community leaders, health professionals, and residents to facilitate open dialogue.
Recent initiatives driven by local organizations have focused on breaking the stigma surrounding addiction, underscoring the importance of recovery and outreach for those affected by substance abuse.
Accredited Drug Testing offers fast, reliable employment screening services in South Bethlehem, PA. Trusted by employers nationwide for accurate results and exceptional service.
Pennsylvania DOT/Non DOT Physicals
Caron Foundation
Gateway Rehab
Universal Health Services
Pro-Act
Lehigh Valley Health Network
Pennsylvania Prevention Project
Lehigh Valley Drug and Alcohol
CRC Health
PA Council on Substance Abuse
Acadia Healthcare
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024