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Accredited Drug Testing facilitates a range of drug and alcohol testing solutions available at our 30 conveniently located facilities in the Southview, Pennsylvania area. We accommodate both DOT and non-DOT urine drug assessments, breath alcohol evaluations, EtG alcohol analysis, and hair drug screenings catering to personal, corporate, and legal requirements. In Southview, PA, we provide expedited results along with SAMSA certified lab analysis, offering same day appointments, with most centers situated just a short distance from your residence or workplace. Our additional offerings include Occupational Health Tests, Clinical Evaluations, and Background Verification.
Dial (800) 221-4291 or register through our website. Simply choose the test you need and find a nearby facility—services are offered for you, your staff, or others. Scheduling a test is swift and straightforward, whether through our scheduling team or via our online system, available at any time. Our efficient process simplifies arranging drug tests near Southview, ensuring minimal hassle.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Southview drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2022, Southview, PA in Washington County reported a 15% increase in opioid-related deaths.
Prescription drug misuse was cited as a primary cause for over 40% of substance abuse treatment admissions in Southview, 2021.
Southview's emergency rooms saw a 20% hike in drug overdose cases between 2020 and 2022.
Approximately 25% of teenagers in Southview reported experimenting with drugs before finishing high school, 2021.
Methamphetamine arrests rose by 30% in Southview, Washington County, in 2023.
In 2022, a county-wide survey in Washington County, including Southview, highlighted that 60% believe drug abuse is the community's biggest issue.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Southview, PA, have implemented stringent drug testing policies to curb workplace substance abuse. Many local companies require pre-employment drug screenings and conduct random tests to ensure a drug-free environment, aligning with guidelines from the Occupational Safety and Health Administration (OSHA).
These efforts extend to providing employee assistance programs focusing on prevention, education, and access to treatment services. Employers work closely with organizations like the Drug Enforcement Administration to align workplace policies with federal regulations.
By actively promoting such initiatives, the local business community in Southview aims to enhance productivity and ensure a safer workplace. This has also led to collaboration with state-level agencies like the Pennsylvania Chamber of Business and Industry to tailor specific guidelines suitable for Southview.
The government of Southview, PA has initiated several programs to combat drug problems in the region. Local authorities collaborate with the Pennsylvania Department of Drug and Alcohol Programs to implement educational seminars and provide resources to the community. For more information on state efforts, visit the Pennsylvania Department of Drug and Alcohol Programs.
Moreover, Washington County has invested in rehabilitation centers and increased funding for mental health services to support those in recovery. The county works in tandem with the Washington County Human Services Department to ensure a multidimensional approach to tackling drug-related issues.
In recent months, Southview, PA has seen significant law enforcement actions against drug activities. A major operation conducted in early 2023 led to multiple arrests relating to a methamphetamine ring that was operating across Washington County.
The operation was a combined effort from the Washington County Drug Task Force and local police departments, highlighting the intensive measures taken to dismantle drug networks. Regular community watch programs have also been set up to monitor and report suspicious activities.
Citizens are encouraged to engage with local law enforcement agencies to share information and assist in drug prevention campaigns. Recent community meetings have reflected a united stance against drug-related issues, aiming to reduce the influence of narcotics in Southview neighborhoods.
Accredited Drug Testing offers fast, reliable employment screening services in Southview, PA. Trusted by employers nationwide for accurate results and exceptional service.
Pennsylvania DOT/Non DOT Physicals
Pennsylvania Department of Drug and Alcohol Programs
OverdoseLife
SAMHSA National Helpline
Narcotics Anonymous
PAAR
Caron Treatment Centers
Gateway Rehab
PA Stop
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024