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At our 37 testing locations in Charlestown, Rhode Island, Accredited Drug Testing offers a full range of drug and alcohol tests. We cater to both DOT and non-DOT specifications, including urine drug testing, breathalyzer tests, EtG, and hair follicle screenings for personal, employment, or legal purposes. Our Charlestown sites provide swift test results with SAMSA certified lab analysis, often accessible the same day. Most facilities are quickly reachable from home or work in Charlestown, RI. We also provide Occupational Health Testing, Clinical Testing, and Background Checks.
Get in touch at (800) 221-4291 or register online to choose your test and find a convenient testing center. Whether for yourself, an employee, or someone else, scheduling is fast and easy. Call our team or use our website to book a test anytime, day or night. Our efficient system makes it simple to set up drug testing services near Charlestown.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Charlestown drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Charlestown, Washington County saw a 12% increase in opioid overdoses in 2022.
Emergency trips in Charlestown County linked to drug overdoses rose by 20% in 2021.
In 2020, Charlestown, RI recorded 30 drug-related arrests.
Charlestown's Washington County reported 5 drug-induced fatalities in 2022.
25% of high school students in Charlestown, Washington County, reported trying marijuana in 2021.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Charlestown, RI prioritize maintaining a drug-free workplace by implementing comprehensive drug testing policies. These policies often comply with state guidelines, such as those outlined by the Rhode Island Department of Labor and Training. Routine screenings are conducted to ensure safety and productivity.
Many organizations mandate pre-employment drug testing as a condition for hiring. Random drug tests may also be initiated to foster a safe work environment. Employers collaborate with local healthcare providers to facilitate these screenings, ensuring all legal and ethical standards are met.
The government of Charlestown, RI has implemented various initiatives to combat drug problems. Collaborations with state-run programs, such as those organized by the Rhode Island Department of Behavioral Healthcare, Developmental Disabilities & Hospitals, play a crucial role. These initiatives aim to provide education, support, and resources for individuals struggling with addiction.
Furthermore, the Charlestown Police Department collaborates with county organizations to conduct awareness campaigns and community outreach. Programs are also established to educate communities about substance abuse and its impact. Through partnerships with entities like the Substance Abuse and Mental Health Services Administration, the government endeavors to reduce drug-related incidences.
In recent months, Charlestown, RI, has seen a significant uptick in local law enforcement efforts targeting drug-related activities. A series of coordinated operations led to multiple arrests, focusing on dismantling street-level distribution networks. Authorities report that these efforts aim to curb the rising tide of opioid abuse, which has become a growing concern for the community and police departments alike.
Local community leaders have praised the ongoing initiatives, emphasizing the importance of collaboration between law enforcement and local residents. Public awareness campaigns have also been launched, aimed at educating youths about the dangers associated with drug abuse. These efforts highlight the town's commitment to creating a safer environment for all its residents.
In one recent bust, officers uncovered a small-scale drug production operation hidden within a residential neighborhood. This discovery has prompted discussions about the need for increased vigilance and reporting of suspicious activities by community members. Law enforcement agencies continue to seek tips and cooperation from the public to address these pressing issues effectively.
The police department in Charlestown is actively working with neighboring towns to address cross-border trafficking concerns. Regional partnerships have been established, facilitating the sharing of information and resources to tackle the complex web of illegal activities. These partnerships are crucial for keeping the entire region free from drug-related crimes.
One of the key challenges facing Charlestown is ensuring that resources allocated for drug rehabilitation and recovery programs meet growing demand. Measures are being taken to improve access to these critical services, with support from state and local government initiatives that aim to provide comprehensive care to those affected by addiction.
Accredited Drug Testing offers fast, reliable employment screening services in Charlestown, RI. Trusted by employers nationwide for accurate results and exceptional service.
Rhode Island DOT/Non DOT Physicals
Rhode Island Attorney General
Rhode Island Prevention Resource Center
BH Link
Alcoholics Anonymous Rhode Island
Rhode Island Hospital
Rhode Island Regional Coalitions
AGA Medical Center
Tides Family Services
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This is by far the easiest way to get my lab work ordered and paid for. The phone calls are short and to the point. They don’t try to push extra sales on you and when I walk in to the clinic I simply show my donor pass and with in a matter of minutes I’m done. I will continue to use ADT in the future.
Jason Jackson - 7/19/2025
Everything was great, the staff was very polite. Thank you.
Olga Petrova - 9/19/2024
The visit here is always the best . The place is always really clean. The employees are super courteous, very polite, and professional. This is the only drug lab I like to go do my drug and alcohol test. I would like to tell them thank you so much for thier excellent performance and job
Eli Gonzalez - 1/4/2025