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Accredited Drug Testing provides a wide range of drug and alcohol testing services in the Valley Springs, South Dakota area, with 29 convenient testing centers. We offer both DOT and non-DOT urine drug tests, breathalyzer tests, EtG alcohol assessments, and hair drug tests for personal, employment, or legal requirements. Rapid results are a hallmark of our services, including SAMSA certified laboratory analysis. Most centers are located just minutes from your home or office, enabling easy access in Valley Springs, SD. We also conduct Occupational Health Testing, Clinical Testing, and Background Checks.
To arrange a test, dial (800) 221-4291 or sign up online. Select the type of test and a nearby center—catering to individual needs, employee screening, or testing another person. With our Fast and Easy scheduling, you can either call our team or book your test online anytime, 24/7. Our efficient system ensures you can easily manage drug testing in Valley Springs without hassle.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Valley Springs drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In Minnehaha County, where Valley Springs is located, drug arrests increased by 8% from 2019 to 2020.
A survey in Valley Springs indicated that 15% of high school students reported using illicit drugs in the past month in 2021.
Prescription drug misuse in Valley Springs resulted in 12% more emergency department visits in 2020 compared to 2019.
In 2020, Minnehaha County reported a 10% increase in opioid-related incidents compared to the previous year.
Methamphetamine use in Valley Springs contributed to 25% of all drug-related arrests in the area in 2021.
In 2021, Valley Springs authorities recorded a 5% increase in drug-related accidents and fatalities.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Valley Springs, SD, often implement stringent drug testing policies to ensure a safe and productive workplace. Many businesses require pre-employment screenings as well as random drug tests for current employees. Such policies are aligned with the U.S. Department of Labor guidelines to maintain a safe working environment.
Some companies participate in drug-free workplace programs which offer educational resources and support for employees. These programs aim to educate the workforce about the dangers of drug abuse and provide assistance to those seeking help to overcome addiction, reinforcing the zero-tolerance approach adopted by many local employers.
The government of Valley Springs, SD, has been proactive in addressing the growing concern of drug abuse. They collaborate with the South Dakota Department of Health to implement preventive measures and educational programs. Efforts also include partnerships with law enforcement agencies to manage and reduce drug-related crimes.
State-funded rehabilitation initiatives have been established to assist those struggling with addiction. These initiatives are designed to provide access to necessary resources and support networks, aiming to reduce the prevalence of drug misuse and its associated impacts on the community.
Valley Springs has experienced several notable drug-related events, highlighting the ongoing challenge of drug abuse in the community. In 2021, a major drug bust in the area led to the seizure of methamphetamines and the arrest of multiple individuals involved in drug trafficking operations.
Local law enforcement, in collaboration with federal agencies, continues to conduct raids and special operations to curb the illegal drug trade. Public awareness campaigns have been launched to inform residents about these efforts and encourage community involvement in reporting suspicious activities.
Accredited Drug Testing offers fast, reliable employment screening services in Valley Springs, SD. Trusted by employers nationwide for accurate results and exceptional service.
South Dakota DOT/Non DOT Physicals
South Dakota Department of Health Resources
South Dakota Statewide Family Support
Helpline Center
Project Turnabout
Face It TOGETHER
Recovery Communities of South Dakota
Avera Addiction Care
Keystone Treatment Center
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Time was running out before my Cdl got downgraded because of a violation I had on clearinghouse. I couldn't find an employer to send me for my return to duty test, but these guys had my test scheduled and done in the same day! They saved my cdl. Thank you again!
Michael Williams - 12/2/2024
I always have a good experience setting up company driver drug screens through ADT. I'm really happy I found them while searching online, they have made my job much easier.
Exodus Heath - 2/13/2025
I use their service for new hire and DOT employee's. Spoke with Taisha Walker this morning, and she was very helpful. She made the process smooth and seamless.
Christina Galdos - 3/9/2025