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Accredited Drug Testing delivers a full suite of alcohol and drug testing solutions across our 35 test locations in the Cumberland Furnace, Tennessee vicinity. We facilitate DOT and non-DOT urine tests, breath alcohol tests, EtG tests, and hair drug screening for individuals, employers, and legal requirements. Quick tests and SAMSA-approved lab analysis are offered in Cumberland Furnace, TN, with immediate service available, and our centers are often just minutes away from your location. Additional services feature Occupational Health Testing, Clinical Testing, and Background Screening.
Dial (800) 221-4291 or register via our website. Choose your desired test and a local test center—services are available for personal, employee, or third-party use. Arranging a test is Swift and Simple, contact our scheduling team or book your test online at any hour. Our efficient process facilitates easy drug test scheduling near Cumberland Furnace.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Cumberland Furnace drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
In 2022, Cumberland Furnace, located in Dickson County, TN, reported a 15% increase in drug-related arrests compared to 2021.
Cumberland Furnace experienced a 13% spike in opioid-related overdose calls in the first quarter of 2023.
In 2023, 8% of Cumberland Furnace's high school students admitted to using prescription drugs recreationally.
The rate of drug overdose deaths in Dickson County, which includes Cumberland Furnace, stood at 27 per 100,000 people in 2022.
In 2022, Cumberland Furnace's drug court program handled over 50 cases involving marijuana and prescription drug abuse.
In Cumberland Furnace, TN, methamphetamine-related incidents saw a 10% increase in 2022 as per county reports.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Cumberland Furnace, TN, are increasingly adopting strict drug testing policies to maintain a safe working environment. Many local businesses require pre-employment drug screenings and random testing to deter substance abuse amongst employees. These initiatives are guided by the recommendations of the Substance Abuse and Mental Health Services Administration (SAMHSA).
Some employers collaborate with local health clinics to facilitate periodic testing and offer support to employees seeking help for addiction. These efforts are crucial in reducing workplace accidents and improving overall productivity. Additionally, businesses often partner with regional coalitions to develop workplace policies that support both prevention and treatment efforts.
The government of Cumberland Furnace, TN, has been actively working to mitigate drug problems within the area. Local initiatives have been bolstered by federal support through grants and collaborations. The Tennessee Department of Mental Health and Substance Abuse Services offers several statewide programs that aid local communities like Cumberland Furnace.
Efforts include increased funding for drug education and prevention programs in schools and enhanced law enforcement training. At the county level, addiction treatment and rehabilitation services have been expanded, with a focus on long-term recovery programs. Additionally, the establishment of support groups within Dickson County has provided residents with essential resources to combat addiction.
In recent years, Cumberland Furnace, TN, has witnessed several significant drug busts. In 2022, a major operation led to the confiscation of a large quantity of methamphetamine and the arrest of multiple individuals linked to its distribution network in Dickson County. This bust was part of a coordinated effort between local law enforcement and the regional drug task force.
Another notable event was the 2023 crackdown on an illicit prescription drug ring operating within the region. The operation underscored the complexities of drug trafficking and the continuous need for vigilance by authorities. Such high-profile busts have been pivotal in disrupting the local drug supply and sending a strong message to communities about the consequences of illegal drug activities.
Accredited Drug Testing offers fast, reliable employment screening services in Cumberland Furnace, TN. Trusted by employers nationwide for accurate results and exceptional service.
Tennessee DOT/Non DOT Physicals
Drug Free TN
Tennessee Department of Mental Health and Substance Abuse Services
Addiction Center Tennessee Rehabs
Substance Abuse and Mental Health Services Administration
Tennessee Pharmacists Association
Centerstone
Jackson Area Council on Alcoholism and Drug Dependency
Tennessee Suicide Prevention Network
NAMI Tennessee
Technology Transfer Center
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024