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Accredited Drug Testing ensures extensive examination services for drugs and alcohol at our 31 locations around Gibbs, Tennessee. We facilitate DOT and non-DOT urine tests, breathalyzer tests, EtG alcohol analyses, and hair follicle tests to serve individuals, employers, and legal requirements. In Gibbs, TN, we provide rapid testing and access to SAMSA-recognized labs, offering same-day service with most centers conveniently located. Our additional services span Occupational Health Tests, Clinical Analysis, and Background Screens.
Dial (800) 221-4291 or visit us online. Just pick your desired test and select the closest center. Testing services are offered for personal, employee, or third-party needs. Scheduling is swift and simple when you contact our team or book online anytime. Our efficient system is designed to help you manage drug testing near Gibbs with ease.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Gibbs drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Gibbs, TN in Knox County reported a 15% increase in opioid-related overdoses from 2020 to 2022.
In 2021, 65% of drug arrests in Knox County involved methamphetamines.
Knox County experiences an average of 200 drug-related hospitalizations annually.
The overdose death rate in Knox County is 29.8 per 100,000 residents as of 2022.
In 2020, 48% of Knox County's substance abuse treatment admissions were for opioids.
Knox County provides drug abuse education in 85% of local schools as of 2023.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Gibbs, TN are vigilant in maintaining a drug-free workplace. Many local businesses enforce mandatory drug testing policies during hiring and conduct random tests to ensure compliance. The OSHA Drug-Free Workplace Program provides guidelines for maintaining a safe environment.
Larger companies often have in-house counseling services or partnerships with rehab centers for employees struggling with substance abuse. This proactive approach not only helps in early detection but also supports employees in their recovery, contributing to a healthier community.
The government of Gibbs, TN has implemented various programs to combat drug issues. Knox County teams up with local authorities to conduct awareness drives, and campaigns promoting drug education in schools. More information can be found at Tennessee Department of Health.
State and federal initiatives focus on providing resources for addiction recovery. The Tennessee government supports rehabilitation efforts through grants and partnerships. Details are available on the Tennessee Department of Mental Health and Substance Abuse Services
In Gibbs, TN, recent collaborative efforts between local law enforcement and community groups have emphasized addressing drug-related incidents. The increased vigilance stems from a concerning rise in opioid-related activities, prompting a series of informative town hall meetings. These gatherings aim to educate residents on recognizing warning signs and the importance of community vigilance in combating drug issues.
Local authorities in Gibbs recently executed a significant drug bust, resulting in the seizure of numerous illegal substances. This event sheds light on the persistent challenge the town faces regarding narcotics distribution. With a focus on dismantling networks, the police emphasize that the community's cooperation remains pivotal in maintaining low crime rates and curbing drug proliferation.
The fight against drugs in Gibbs saw a pivotal moment as a local advocacy group partnered with schools to launch prevention programs. These initiatives primarily target young people, providing education on the dangers of substance abuse. By fostering awareness and offering guidance, these programs aim to deter young residents from engaging in drug-related activities, ultimately reducing future incidences.
In a proactive approach, the Gibbs community organized a drug take-back event, allowing locals to dispose of unused or expired medications safely. This event drew significant participation, reflecting the town's commitment to circumvent potential misuse of prescription drugs. Such initiatives, organized with assistance from law enforcement, are essential in diminishing drug accessibility and promoting public safety.
Local law enforcement in Gibbs has recently bolstered efforts by incorporating technology into its crime-fighting arsenal. The implementation of advanced surveillance systems and real-time data analysis tools assists officers in tracking and predicting drug trafficking patterns. This strategic enhancement not only fortifies the town's defenses against drug crimes but also strengthens ties with neighboring communities facing similar challenges.
Accredited Drug Testing offers fast, reliable employment screening services in Gibbs, TN. Trusted by employers nationwide for accurate results and exceptional service.
Tennessee DOT/Non DOT Physicals
Tennessee Department of Behavioral Health
Knox County Health Department
Tennessee Mental Health and Substance Abuse Services
National Substance Abuse and Mental Health Services Administration
Tennessee o-drug Crisis Response
Tennessee Alcohol and Drug Association
McMinn County Health Department
Tennessee Recovery Coalition
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024