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Accredited Drug Testing provides a full range of drug and alcohol testing services at 30 locations around Seymour, Tennessee. Catering to individual, workplace, and legal requirements, we offer DOT and non-DOT urine tests, breath alcohol evaluations, EtG alcohol screenings, and hair drug tests. Rapid results testing and SAMSA certified lab analysis are offered, with most Seymour facilities conveniently situated near your home or workplace. Additional offerings include Occupational Health Assessments, Clinical Testing, and Background Checks.
To set up a test, dial (800) 221-4291 or register online. With just a few clicks, choose your desired test and a center close by—ideal for personal, employee, or third-party testing. Booking is swift and straightforward; contact our scheduling team or schedule anytime online. Our efficient process makes organizing drug testing in Seymour simple and accessible.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Seymour drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
DOT Drug Testing and Requirements
DOT Employer Drug Policy Development
If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Seymour, TN, in Sevier County, recorded 120 drug-related arrests in 2022, according to local law enforcement.
A 2022 survey showed 8% of high school students in Seymour, TN, reported using illicit drugs in the past month.
In 2021, Sevier County, where Seymour is located, saw a 15% increase in opioid-related overdoses.
Approximately 25% of adults in Sevier County, including Seymour, reported excessive drinking, contributing to drug abuse issues.
Seymour, TN, recorded 30 opioid overdose deaths in 2022, as reported by the Sevier County Health Department.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
Employers in Seymour, TN, recognize the importance of maintaining a drug-free workplace and have implemented strict drug testing policies to ensure safety and productivity. Many businesses utilize pre-employment drug screenings and random checks to deter substance abuse among employees.
The Tennessee Drug-Free Workplace Program, accessible via the Tennessee Department of Labor and Workforce Development TDLWD, provides guidelines and support for employers in Seymour seeking to implement or enhance their drug testing policies.
The government in Seymour, TN, has been actively working to address drug problems through various initiatives. The Sevier County Drug Coalition Sevier County Drug Coalition aims to educate the community about the dangers of drug abuse and provides resources for prevention and recovery.
Furthermore, the Tennessee Department of Mental Health and Substance Abuse Services TDMHSAS has implemented state-wide programs that assist local communities, including Seymour, in combating drug abuse through education, treatment options, and support networks for families.
Police in Seymour, TN, recently conducted a significant drug bust, seizing large quantities of illegal substances. This operation was part of a broader initiative aiming to curb drug trafficking in the area. Authorities arrested several individuals believed to be key figures in a local distribution network. The raid has been considered a success in the ongoing efforts to reduce drug-related crime.
In another incident, the Seymour community was shaken by the discovery of a clandestine methamphetamine lab. Law enforcement officials acted on a tip-off from concerned residents, leading to the prompt dismantling of the illegal operation. This event has highlighted the challenges local authorities face in combating the production and distribution of meth.
The rise in opioid-related arrests has prompted Seymour, TN, to increase its focus on community outreach programs. These programs aim to educate the public about the dangers of opioid misuse and provide necessary resources for those seeking treatment. The ongoing initiatives reflect a commitment to addressing the opioid crisis at both the law enforcement and community levels.
Recent collaborations between Seymour law enforcement agencies and neighboring counties have led to improved intelligence sharing on drug-related activities. This cooperation has been instrumental in identifying cross-border drug trafficking patterns and ensuring swift action against organized crime groups. Such partnerships are pivotal in the strategic fight against illegal narcotics.
Accredited Drug Testing offers fast, reliable employment screening services in Seymour, TN. Trusted by employers nationwide for accurate results and exceptional service.
Tennessee DOT/Non DOT Physicals
Sevier County Drug Coalition
Tennessee Department of Mental Health and Substance Abuse Services
Tennessee Drug-Free Workplace Program
Tennessee Department of Health: Drug Overdose
Hosanna House
Cornerstone of Recovery
Metro Drug Coalition
Helen Ross McNabb Center
Ridgeview Behavioral Health Services
NAMI Tennessee
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024