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Accredited Drug Testing provides a full range of drug and alcohol screening services across 32 locations near Chandler, Texas. We cater to individuals and businesses with both DOT and non-DOT urine drug tests, breath alcohol screenings, EtG alcohol tests, and hair drug analyses. Our services in Chandler, TX offer quick result turnarounds and SAMSA certified lab analysis, available the same day. Testing locations are conveniently close to your residence or workplace. We also provide Occupational Health Testing, Clinical Testing, and Background Checks.
Contact us at (800) 221-4291 or register through our online system. Pick your desired test and choose the most convenient location for personal, employee, or third-party testing. Scheduling is quick and straightforward. You can reach our scheduling team by phone or arrange your test online anytime. Our efficient and accessible process simplifies setting up drug testing near Chandler.
* You must register by phone or online to receive your donor pass/registration prior to proceeding to the testing center. You must bring a valid government issued ID along with the registration/barcode number which was sent to you by email.
When you're searching for drug testing near me or drug testing locations, we provide a simple and convenient process to find a drug and alcohol testing location near you that is certified to provide all of your drug and alcohol testing needs.
At our Chandler drug testing collection sites, Accredited Drug Testing provides one of the widest selections of drug and alcohol testing services available. Whether you're an employer, attorney, court, or private individual, we offer both DOT and non-DOT testing options—ranging from rapid tests to comprehensive lab-based screenings—capable of detecting nearly any substance.
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If you're an employer needing to test 25 or more employees and looking to save time and money, we offer mobile on-site drug testing where we come to you. Call us today for more information.
Chandler, TX, in Henderson County, reported a 15% increase in opioid-related overdoses from 2021 to 2022.
As of 2022, Chandler, TX saw a 20% rise in methamphetamine-related arrests in Henderson County.
In Chandler, TX, Henderson County, emergency room visits due to drug overdoses increased by 10% in 2022.
The 2022 survey revealed that 8% of high school students in Chandler, TX, Henderson County, admitted to using illegal drugs.
Chandler, TX has seen a 5% increase in drug trafficking incidents in Henderson County from 2021 to 2022.
In 2022, Chandler, TX, Henderson County, reported an increase in drug-related property crimes by 12%.
Drug elimination is the sum of the processes of removing an administered drug from the body. In the pharmacokinetic ADME scheme (absorption, distribution, metabolism, and excretion), it is frequently considered to encompass both metabolism and excretion. Hydrophobic drugs, to be excreted, must undergo metabolic modification making them more polar. Hydrophilic drugs, on the other hand, can undergo excretion directly, without the need for metabolic changes to their molecular structures.
Although many sites of metabolism and excretion exist, the chief organ of metabolism is the liver, while the organ primarily tasked with excretion is the kidney. Any significant dysfunction in either organ can result in the accumulation of the drug or its metabolites in toxic concentrations.
A variety of other factors impact elimination — intrinsic drug properties, such as polarity, size, or pKa. Also other factors include genetic variation among individuals, disease states affecting other organs, and pathways involved in the way the drug distributes through the body, such as first-pass metabolism.
Drug elimination is the removal of an administered drug from the body. It is accomplished in two ways, either by excretion of an unmetabolized drug in its intact form or by metabolic biotransformation followed by excretion. While excretion is primarily carried out by the kidneys, other organ systems are involved as well. Similarly, the liver is the primary site of biotransformation, yet extrahepatic metabolism takes place in a variety of organ systems affecting multiple drugs.
Given the multiple organ systems and the variety of metabolic transformations present, drug elimination can entail a significant degree of complexity. Hydrophilic drugs are typically directly excreted by the kidneys, while hydrophobic drugs undergo biotransformation before excretion. The purpose here is twofold – biotransformation serves both detoxify the exogenous substances as well as to increase their hydrophilicity, ensuring their elimination via the kidneys.
Two broad metabolic pathways of hepatic drug transformation exist. Phase I is the direct modification of the target molecule, whereas phase II entails conjugation of the target to a polar molecule of low molecular weight. Phase I prepare the drug to enter phase II, but single-phase metabolism also exists.
Phase I involves oxidation, reduction, and hydrolysis of the exogenous molecule. These reactions are accomplished by hepatic microsomal enzymes, which reside in the smooth endoplasmic reticulum of the hepatocytes. Best known among them is the cytochrome P450 system, whose enzymes are predominantly involved in oxidative metabolism. Within the cytochrome P450 family (CYP), the enzyme responsible for the metabolism of more than 50% of existing drugs is the CYP3A4. Its activity encompasses various classes of medications, including opioids, immunosuppressants, antihistamines, and benzodiazepines. The enzymes can also be induced or inhibited by a variety of substances they interact with, including pharmaceuticals. The increase in metabolic activity with CYP induction results in a diminished activity of drugs targeted by that particular isoform. Conversely, CYP inhibition will result in increased drug plasma concentration, potentially leading toxicity. The CYP3A4 is induced by phenytoin, phenobarbital, and St. John's wort, while diltiazem, erythromycin, and grapefruit inhibit it. Caution is, therefore, necessary when administering CYP3A4-metabolized drugs in the presence of any of the inhibitors or inducers.
Phase II consists of covalent bonding of polar groups to nonpolar molecules to render them water-soluble and allow renal or biliary excretion. Target molecules enter phase II directly or via initial processing through phase I. A variety of polar adjuncts is transferred, including amino acids, glucuronic acid, glutathione, acetate, and sulfate. Glucuronidation is one of the major pathways of phase II biotransformation. The UDP-glucuronosyltransferase (UGT) enzyme family performs this activity. Typically, glucuronide derivatives possess less or no activity of the original drug, but in some cases, pharmacologically active compounds result. Morphine-6-glucuronide is a phase II metabolite of morphine with significant analgesic activity. As with the CYP enzymes, inducers, and inhibitors of phase II, enzymes exist and may influence the efficacy of drugs that rely on conjugation before excretion.
The first-pass effect is a feature of hepatic metabolism that also plays a role in the elimination of multiple drugs. Here, the enteric consumed drugs are exposed directly to the liver via the portal vein, where they undergo biotransformation before entering the systemic circulation. This activity reduces the bioavailability and needs to be factored into the dose administered to the patient. Intravenously administered drugs are not subject to the first-pass effect.
Extrahepatic drug metabolism takes place in the GI tract, kidneys, lungs, plasma, and skin.
Renal excretion completes the process of elimination that begins in the liver. Polar drugs or their metabolites get filtered in the kidneys and typically do not undergo reabsorption. They subsequently get excreted in the urine. Urinary pH has a significant impact on excretion, as drug ionization changes depending on the alkaline or acidic environment. Increased excretion occurs with weakly acidic drugs in basic urine and weakly basic drugs in acidic urine.
Excretion in the bile is another significant form of drug elimination. The liver can actively secrete ionized drugs with a molecular weight greater than 300 g/mol into bile, from where they reach the digestive tract and are either eliminated in feces or reabsorbed as part of the enterohepatic cycle.
Other pathways of excretion include the lungs, breast milk, sweat, saliva, and tears
In Chandler, TX, many employers have recognized the critical importance of maintaining a drug-free workplace. Companies have adopted stringent drug-testing policies, often requiring pre-employment and random drug tests to safeguard productivity and safety. Such policies are particularly emphasized in industries where safety is paramount, including manufacturing and construction.
Employers in Chandler also adhere to state guidelines from the Texas Workforce Commission, ensuring compliance with applicable laws while promoting a healthy working environment. Additionally, some businesses provide access to employee assistance programs that offer confidential support and counseling for those dealing with substance abuse issues, reflecting a comprehensive approach to employee wellness.
The city of Chandler, TX, located in Henderson County, has implemented several government initiatives aimed at combating drug abuse. One such effort includes increased funding for the Chandler Police Department to enhance their capabilities in drug detection and prevention. Additionally, the local government works closely with state agencies like the Texas Department of Public Safety to gather data and strategize effectively. Several community outreach programs have been established to educate the public about the risks associated with drug abuse and provide resources for those in need.
An emphasis on rehabilitation is also part of the government's approach, promoting collaboration between local health departments and organizations like the Texas Health and Human Services. These programs focus on providing counseling services, support groups, and treatment options to residents battling addiction. The commitment to addressing drug-related issues in Chandler highlights ongoing efforts to ensure community safety and health.
In recent years, Chandler, TX, has witnessed a few significant drug busts that have garnered attention in Henderson County. Notably, in 2022, a local law enforcement operation led to the seizure of several kilograms of methamphetamine, coupled with the arrest of multiple individuals believed to be part of an organized drug ring. These coordinated efforts underscore the police department's commitment to reducing drug trafficking in the area.
Public awareness events are also part of the strategy to combat drug issues in Chandler. Local organizations frequently collaborate with law enforcement to host seminars and workshops aimed at educating the community about the dangers of drug use and how to identify signs of abuse. Additionally, these events often provide resources for those seeking help with addiction, emphasizing a holistic community-centered approach to the drug problem.
Accredited Drug Testing offers fast, reliable employment screening services in Chandler, TX. Trusted by employers nationwide for accurate results and exceptional service.
Texas Drug Helpline
SAMHSA National Helpline
Texas Council on Alcohol and Drug Addiction
Texas Department of State Health Services Substance Abuse
Partners Behavioral Health Management
Texas Health and Human Services
Narcotics Anonymous
Alcoholics Anonymous
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Trish last week and Tatiana this week, very fun and easy folks to deal with. Well be using them more and more in the future.
Tom O - 12/19/2024
Trish was amazing and got me through the sytem very fast and swift. I had a hard time hearing her a couple of times, but she was super sweet and helpful throughout the process. Highly recommend her!
Sophia Schutze - 6/19/2024
I've had to use this service twice for out of state physicians we've hired and both times it was super easy. Both customer service reps I spoke with were super helpful and courteous. I won't hesitate to use their service again if needed.
Alicia Rau - 6/19/2024